Physiological sexual disorder

This study will test whether living in a self-contained, AI-managed community (called a Microcity) can improve mental health and reduce addiction in adults with conditions like autism, ADHD, substance use disorders, and behavioral addictions. Up to 1 million participants will liv…

This trial tests whether MRI-guided High-Intensity Focused Ultrasound (HIFU) can ease symptoms of adenomyosis, a condition where uterine tissue grows into the muscle wall, causing pain and heavy bleeding. Researchers plan to enroll 20 women aged 18 and older who have adenomyosis …

This trial tests whether transcutaneous tibial nerve stimulation (TTNS), a non-invasive nerve stimulation technique, can improve sexual function and pelvic alignment in women aged 25–35 who have both low back pain and female sexual dysfunction. Participants will receive TTNS alon…

Researchers are testing a six-week, nurse-led program that helps Chinese prostate cancer survivors and their female partners talk about sex, rebuild intimacy, and cope together after treatment. About 72 couples join the study, with half receiving the program plus standard survivo…

This study tests a program called SUFICS-PACT for prostate cancer survivors who have sexual or urinary problems after treatment. The program includes screening, counseling from mental health professionals, and close follow-up. About 200 participants will be randomly assigned to r…

This study will test whether pelvic floor-focused clinical Pilates exercises can reduce pain, improve self-esteem, body image, and quality of life in women with dyspareunia (painful intercourse). Twenty sexually active women aged 18-55 will participate. The goal is to see if this…

This study follows 130 men with unfavorable intermediate-risk prostate cancer to see how a combination of targeted radiation (SBRT) and 6 months of hormone therapy (ADT) impacts their sexual function. Researchers measure erectile function before treatment and again after 24 month…

This study tests a daily testosterone gel to see if it can safely improve sexual interest and arousal in women going through menopause. Researchers will compare the gel to a placebo in 150 women aged 40-65 who have been diagnosed with low sexual desire. The goal is to provide a m…

This study tests whether an internet-based physical activity program can improve sexual dysfunction in women with relapsing-remitting multiple sclerosis. Thirty women with MS and sexual problems will use a website and have video chats with a coach to increase their physical activ…

This Phase 2 study tests a gel called BZ371A on 174 women with sexual arousal disorder. The gel is applied before sexual activity to see if it increases arousal, desire, and lubrication compared to a placebo. The goal is to find a safe and effective option for women struggling wi…

This study tests a new app that provides education, exercises, and mindfulness tools for people with sexual dysfunction who are on an NHS waiting list for therapy. The app uses artificial intelligence to personalize the experience. Researchers will measure changes in sexual funct…

This study looks at the long-term urinary, sexual, and bowel health of people aged 7 to 25 who had surgery for Hirschsprung disease as young children. Hirschsprung disease is a rare birth defect where part of the large intestine lacks nerve cells, causing blockages. Surgery remov…