Pheochromocytoma-paraganglioma
MONDO:0035540A rare neuroendocrine tumor arising from chromaffin cells of the adrenal medulla (pheochromocytoma) or from sympathetic and parasympathetic ganglia (paraganglioma). These tumors are most often benign and may produce catecholamines in excess causing hypertension and sometimes severe acute cardiovascular complications.
1457 clinical trials for this condition and its sub-types, 18 tagged with Pheochromocytoma-paraganglioma itself.
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Rare cancer hope: immune drug shows promise in phase 2 trial
Disease control OngoingThis study tested a drug called pembrolizumab in 157 people with rare cancers that had spread or couldn't be removed. The drug works by helping the body's immune system attack the cancer. The main goal was to see how many patients were alive and their cancer hadn't grown after 27…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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New hope for rare tumors? drug axitinib tested in small trial
Disease control OngoingThis phase II trial tests the drug axitinib in 6 adults with metastatic or inoperable pheochromocytoma or paraganglioma, rare tumors of the adrenal glands or nerve tissue. Axitinib works by blocking blood vessel growth that feeds tumors. The main goal is to see how many patients'…
Phase 2 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Heart risks in adrenal tumor patients under the microscope
Knowledge-focused By invitation onlyThis study follows 150 patients with functional adrenal tumors to see how their heart and blood pressure change before and after surgery. Researchers will use heart ultrasounds and blood pressure monitoring to understand recovery and risks. The goal is to help doctors choose bett…
Sponsor: Peking University First Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:09 UTC