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Personality disorder
MONDO:0002028A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work.
Also known as: personality disorder, personality disorder (disease)
172 clinical trials for this condition and its sub-types, 24 tagged with Personality disorder itself.
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Sub-types of Personality disorder
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Borderline personality disorder 74 trials
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Schizotypal personality disorder 20 trials
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Antisocial personality disorder 12 trials
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Narcissistic personality disorder 2 trials
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Avoidant personality disorder 1 trial
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Dependent personality disorder 0 trials
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Histrionic personality disorder 0 trials
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Paranoid personality disorder 0 trials
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Schizoid personality disorder 0 trials
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Can rewriting your life story improve mental health? small trial tests new therapy
Symptom relief OngoingThis study tests a therapy called RETELL that helps people with severe mental illness explore and reshape their life stories. The goal is to improve personal recovery, quality of life, and identity. Twenty adults with conditions like schizophrenia, bipolar disorder, or PTSD will …
Sponsor: University of Aarhus • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Can talking about your thoughts help treat eating disorders?
Symptom relief OngoingThis pilot study is testing a type of talk therapy called Metacognitive Interpersonal Therapy (MIT-ED) for adults with various eating disorders, including those who are underweight. The therapy aims to help people understand and manage the negative thoughts and feelings that driv…
Sponsor: GLORIA FIORAVANTI • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Pen and paper power: journaling may supercharge psychotherapy
Symptom relief By invitation onlyThis study looks at whether adding a structured therapy journal to standard cognitive behavioral therapy (CBT) helps people with mental health conditions like depression, anxiety, or eating disorders feel better faster. About 80 adults in outpatient therapy will be randomly assig…
Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Can online therapy plus In-Person sessions help personality disorders?
Symptom relief OngoingThis study is testing a new type of therapy called Blended Dynamic Interpersonal Therapy (B-DIT) for adults with personality disorders. The therapy mixes face-to-face sessions with online modules over several months. The goal is to see if this approach is acceptable to patients a…
Sponsor: De Viersprong • Aim: Symptom relief
Last updated Jun 26, 2026 15:50 UTC
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Study on teen body drawings withdrawn before starting
Knowledge-focused CancelledThis study was designed to explore how adolescents with and without borderline personality disorder represent their inner body through drawings, interviews, and questionnaires. It aimed to identify differences in the types and number of organs drawn, as well as emotional or symbo…
Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Real-World therapy study seeks to unlock secrets of personality disorder treatment
Knowledge-focused OngoingThis study follows 91 adults with personality disorders who are receiving intensive psychodynamic therapy in a real-world clinic. Researchers want to see if the therapy works as well outside of strict research settings and what specific factors lead to improvement. The goal is to…
Sponsor: KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can we predict who will succeed in alcohol group therapy?
Knowledge-focused OngoingThis study follows 120 people in group therapy for alcohol use disorder to see which patient factors—like mental health, drinking severity, personality, or thinking skills—predict who finishes treatment and stays sober a year later. Researchers hope to learn how to match patients…
Sponsor: The Hospital of Vestfold • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:22 UTC