Patent ductus arteriosus

MONDO:0011827

A congenital defect characterized by the failure of the ductus arteriosus to close soon after birth. As a consequence, blood from the aorta mixes with blood from the pulmonary artery. If untreated, it may lead to congestive heart failure.

Also known as: PDA, patent ductus arteriosus, patent ductus botalli, persistent patency of the arterial duct, patency of the ductus arteriosus, patent ductus arteriosus familial (type)

102 clinical trials for this condition and its sub-types, 28 tagged with Patent ductus arteriosus itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Vascular disorder (10728) ↑ Cardiogenetic disease (618) ↑ Congenital heart disease (419)

Sub-types of Patent ductus arteriosus

Including sub-types (102) Tagged with Patent ductus arteriosus (28)

Trials to join now! 9 Not yet recruiting 3 Not yet finished but already full! 6 Completed 9 Terminated 1

Abandoned study: can a common painkiller help close a tiny heart vessel in preemies?

Disease control Stopped early

This study tested whether adding acetaminophen to standard ibuprofen treatment could better close a blood vessel (ductus arteriosus) that stays open too long in very premature infants. The trial was planned for preterm babies born at or before 27 weeks and 6 days who needed breat…

Phase 2 • Sponsor: University of South Alabama • Aim: Disease control

Last updated Jun 27, 2026 12:26 UTC

Patent ductus arteriosus

Where it sits in the disease tree

Abandoned study: can a common painkiller help close a tiny heart vessel in preemies?