Paraneoplastic syndrome
MONDO:0021073A classification for rare disorders of diverse organ systems (endocrine, neuromuscular, gastrointestinal, renal, dermatologic, rheumatologic, hematologic) that are affected by substances secreted by a distant neoplasm but not by the action of the neoplasm itself metastasizing to that organ or tissue. Less than 1 % of neoplasms are associated with these syndromes. An immune-mediated response to neoplasm-elaborated proteins may be the cause of these syndromes. Additionally, their manifestation may signal the presence of an occult neoplasm, potentially at an earlier stage of disease thereby leading to a better clinical outcome. Constitutional signs may include fever, night sweats, anorexia and cachexia. Clinical course is usually progressive. Prognosis is variable depending on the effective treatment of the underlying neoplasm.
Also known as: paraneoplastic syndrome
20 clinical trials for this condition and its sub-types, 1 tagged with Paraneoplastic syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Paraneoplastic syndrome
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Paraneoplastic neurologic syndrome 1 trial · 15 incl. sub-types
7 sub-types
- POEMS syndrome 8 trials
- Lambert-Eaton myasthenic syndrome 4 trials
- Opsoclonus-myoclonus syndrome 2 trials
- Paraneoplastic cerebellar degeneration 1 trial
- Cancer-associated retinopathy 0 trials
- Paraneoplastic limbic encephalitis 0 trials Sub-types →
- Paraneoplastic polyneuropathy 0 trials
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Parneoplastic endocrine syndrome 0 trials · 11 incl. sub-types
2 sub-types
- POEMS syndrome 8 trials
- Oncogenic osteomalacia 3 trials
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Paraneoplastic hematological syndrome 0 trials · 9 incl. sub-types
2 sub-types
- POEMS syndrome 8 trials
- Humoral hypercalcemia of malignancy 1 trial
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Paraneoplastic renal syndrome 0 trials · 3 incl. sub-types
1 sub-type
- Oncogenic osteomalacia 3 trials
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Paraneoplastic cutaneous syndrome 0 trials
1 sub-type
- Paraneoplastic pemphigus 0 trials
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Paraneoplastic rheumatic syndrome 0 trials