Paraneoplastic cerebellar degeneration

MONDO:0044877

A rare, immune-mediated disorder characterized by cerebellar degeneration due to the presence of an often undetected malignancy (usually carcinoma or lymphoma) in an anatomic site other than the cerebellum. Signs and symptoms include progressive ataxia, dysarthria, and nystagmus.

Also known as: paraneoplastic cerebellar degeneration

3 clinical trials for this condition and its sub-types, 1 tagged with Paraneoplastic cerebellar degeneration itself.

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Where it sits in the disease tree

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Part of

↑ Cerebellar degeneration (150) ↑ Paraneoplastic neurologic syndrome (15)

Including sub-types (3) Tagged with Paraneoplastic cerebellar degeneration (1)

Trials to join now! 1 Not yet recruiting 2

Blood samples could unlock secrets of rare brain diseases

Knowledge-focused Recruiting now

This study collects blood samples from 1000 people with rare neurological diseases that may be autoimmune. Researchers will use the samples to find new biomarkers and autoantibodies, which could help diagnose and treat these conditions in the future. Participants give extra blood…

Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused

Last updated Jun 27, 2026 11:02 UTC

Paraneoplastic cerebellar degeneration

Where it sits in the disease tree

Blood samples could unlock secrets of rare brain diseases