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Papillon-Lefevre disease
MONDO:0009490Papillon-Lefevre syndrome (PLS) is a rare ectodermal dysplasia characterized by palmoplantar keratoderma associated with early-onset periodontitis.
Also known as: PLS, Papillon Lefèvre Syndrome, keratosis palmoplantar-periodontopathy syndrome, Keratoris palmoplantaris with periodontopathia, PALS, PAPILLON-Lefevre syndrome, Papillon-LEFèvre syndrome, Pls
26 clinical trials for this condition and its sub-types, 5 tagged with Papillon-Lefevre disease itself.
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Could a Mail-In breath test diagnose bad breath?
Diagnosis CompletedThis study explores whether gas samples from the mouth can be collected and analyzed up to 7 days later to diagnose halitosis (bad breath). Researchers will take breath samples from 100 adults with gum disease and measure volatile sulfur compounds—the molecules responsible for ba…
Sponsor: University Hospital, Strasbourg, France • Aim: Diagnosis
Last updated Aug 21, 2026 00:00 UTC
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Smartphone AI could spot gum disease with a single photo
Diagnosis CompletedThis study tests an artificial intelligence system that measures the width of keratinized gingiva (a type of gum tissue) from smartphone photos. Researchers will compare the AI's measurements to those made by dental experts to see how accurate the tool is. The goal is to make gum…
Sponsor: Al-Azhar University • Aim: Diagnosis
Last updated Jul 10, 2026 00:00 UTC
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Gum disease and quality of life: new study seeks answers
Knowledge-focused CompletedThis study looks at how oral hygiene habits and gum health affect quality of life in 160 adults. Participants will have a dental exam and fill out a questionnaire about how their mouth feels day-to-day. No treatment is given—the goal is simply to understand the connection between…
Sponsor: Abant Izzet Baysal University • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Coffee drinkers: your morning cup may impact your gums!
Knowledge-focused CompletedThis study examined 318 adults to see if coffee drinking habits are linked to gum health. Participants were grouped by gum condition (healthy, gingivitis, or periodontitis) and asked about their coffee intake. Researchers measured plaque, bleeding, and gum pocket depth to find an…
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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Wearable sensors monitor ALS progression in new study
Knowledge-focused CompletedThis study tests whether wearable sensors and digital home tasks can track changes in movement, speech, and falls in people with ALS. About 20 participants will wear neck and wrist sensors and complete speech and handwriting tests over 48 weeks. The goal is to see if these digita…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Gum health tied to dental Know-How in new turkish study
Knowledge-focused CompletedThis completed study looked at 108 Turkish adults to see if understanding dental health information is linked to gum health. Participants took a reading test about dentistry and had a dental exam. The goal was to find out if people with lower health literacy have worse gum diseas…
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Smoking linked to worse gum health in new study
Knowledge-focused CompletedThis completed study looked at how smoking affects gum health in 484 adults. Researchers compared current smokers to non-smokers by measuring plaque, gum bleeding, pocket depth, and gum recession. The goal was to better understand the link between smoking and periodontal disease.
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC