Pancreatic neuroendocrine neoplasm
MONDO:0005815A neoplasm with neuroendocrine differentiation that arises from the pancreas. It includes neuroendocrine tumors (low and intermediate grade) and neuroendocrine carcinomas (high grade).
Also known as: PNEN, endocrine pancreas neoplasm, endocrine pancreas neoplasm (disease), endocrine pancreas tumor, endocrine pancreas tumour, neoplasm of endocrine pancreas, pancreatic NEN, pancreatic endocrine neoplasm
1563 clinical trials for this condition and its sub-types, 9 tagged with Pancreatic neuroendocrine neoplasm itself.
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Sub-types of Pancreatic neuroendocrine neoplasm
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Pancreatic neuroendocrine tumor 60 trials · 77 incl. sub-types
11 sub-types
- Functional pancreatic neuroendocrine tumor 1 trial · 14 incl. sub-types Sub-types →
- Pancreatic insulin-producing neuroendocrine tumor 0 trials · 13 incl. sub-types Sub-types →
- Somatostatinoma 6 trials
- Pancreatic neuroendocrine tumor G1 1 trial · 5 incl. sub-types Sub-types →
- Non-functional pancreatic neuroendocrine tumor 4 trials Sub-types →
- Glucagonoma 2 trials
- Pancreatic gastrin-producing neuroendocrine tumor 2 trials Sub-types →
- PPoma 1 trial
- VIPoma 1 trial Sub-types →
- GRFoma 0 trials
- Pancreatic delta cell neuroendocrine tumor 0 trials Sub-types →
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Pancreatic endocrine carcinoma 12 trials
2 sub-types
Most studied deeper sub-types
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New surgery aims to cut pancreatic leak and diabetes risk
Disease control Recruiting nowThis study tests a surgery called total pancreatectomy with islet autotransplantation (TPIAT) in 30 adults with certain pancreatic tumors who are at high risk for a dangerous leak after standard surgery. The procedure removes the entire pancreas and transplants the insulin-making…
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New drug combo targets Hard-to-Treat pancreatic tumors
Disease control Recruiting nowThis early-phase trial is testing whether combining two targeted therapies—sunitinib malate and Lutathera—is safe for people with advanced pancreatic neuroendocrine tumors that have spread or cannot be removed. Sunitinib blocks signals that help tumors grow, while Lutathera deliv…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Could chemo after surgery keep pancreatic cancer at bay?
Disease control Recruiting nowThis study looks at whether giving two chemotherapy drugs (capecitabine and temozolomide) after surgery can prevent or delay the return of high-risk pancreatic neuroendocrine tumors. About 141 people who have had their tumor removed will be randomly assigned to receive the drugs …
Phase 2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Do Younger-Age pancreatic tumors behave differently? a new study digs in
Knowledge-focused Recruiting nowThis study looks back at medical records from 600 people to compare pancreatic neuroendocrine tumors (PanNETs) that appear at a younger age versus those that appear later in life. Researchers want to see if these two groups have different risk factors, tumor features, metabolic c…
Sponsor: Qilu Hospital of Shandong University • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Massive pancreas tissue bank launches to unlock disease secrets
Knowledge-focused Recruiting nowThis study collects blood, tissue, and health information from 20,000 people with pancreas diseases like pancreatic cancer, pancreatitis, or cysts. The goal is to create a large database and sample bank that researchers can use to better understand these conditions and develop be…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can genes predict pancreatic tumor risk? new study aims to find out
Knowledge-focused Recruiting nowThis study looks at the genes of 300 people with pancreatic neuroendocrine tumors to find inherited mutations that may be linked to the disease. Participants provide a blood or saliva sample for genetic testing. The goal is to learn more about genetic causes, not to test a new tr…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC