Pancreatic intraductal papillary-mucinous neoplasm
MONDO:0004286A usually slow-growing epithelial neoplasm with ductal differentiation that arises from the exocrine pancreas and grows mostly within the pancreatic ducts. Grossly, it is characterized by the presence of intraductal masses. Morphologically, there is proliferation of mucin-producing cells within the pancreatic ducts, intraductal accumulation of mucin, and a papillary growth pattern. It may be associated with the presence of an invasive carcinoma. It usually occurs in older patients. Signs and symptoms include epigastric pain, weight loss, jaundice, chronic pancreatitis, and diabetes mellitus.
Also known as: IPMN, pancreatic IPMN, pancreatic intraductal papillary-mucinous neoplasm, pancreatic intraductal papillary-mucinous tumor, pancreatic intraductal papillary-mucinous tumour, intraductal papillary mucinous neoplasm
2909 clinical trials for this condition and its sub-types, 38 tagged with Pancreatic intraductal papillary-mucinous neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pancreatic intraductal papillary-mucinous neoplasm
-
Could a simple wash during surgery extend lives of pancreatic cancer patients?
Disease control OngoingThis study tests if washing the abdomen with distilled water or saline right after removing a pancreatic tumor can help patients live longer. About 845 adults having surgery for pancreatic or related cancers are randomly assigned to one of three groups: washing with saltwater, wa…
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
-
Walk and eat to beat pancreatic cancer? tiny trial tests lifestyle fix
Disease control OngoingThis study tests whether a 6-month program of exercise tracking and nutrition coaching is practical and acceptable for people with pancreatic cysts that raise cancer risk. Twenty-four participants will use a Fitbit and meet with counselors to increase activity and improve diet. T…
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
-
Can a new ultrasound technique spot hidden pancreatic cancers earlier?
Diagnosis By invitation onlyThis study evaluates a new diagnostic procedure called LINFU® to see if it can detect early pancreatic cancer and precancerous changes (dysplasia) in people with intraductal papillary mucinous neoplasm (IPMN), a condition that raises the risk of pancreatic cancer. Participants wi…
Sponsor: Adenocyte, LLC • Aim: Diagnosis
Last updated Aug 08, 2026 00:03 UTC
-
Hope for pancreatic cancer prevention: old drug, new trial
Prevention OngoingThis study tests whether the anti-inflammatory drug sulindac can prevent high-risk pancreatic cysts (IPMNs) from progressing to pancreatic cancer. About 100 adults with these cysts will receive either sulindac or a placebo for up to 3 years, alongside standard monitoring. The goa…
Phase 2 • Sponsor: Duke University • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
-
Vitamin e derivative tested to halt pancreatic cyst growth
Prevention OngoingThis study tests whether a natural compound called delta-tocotrienol (a form of vitamin E) can prevent pancreatic cysts (IPMNs) from growing or turning into cancer. About 4 adults with IPMNs that are being watched but not yet dangerous will receive either the supplement or a plac…
Phase 2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Prevention
Last updated Jun 27, 2026 07:57 UTC
-
Camera probe spots hidden pancreatic lesions during surgery
Knowledge-focused OngoingThis study tests a tiny camera called SpyGlass that doctors insert into the pancreatic duct during surgery for a condition called IPMN (a type of cyst that can turn into cancer). The goal is to see if the camera can find small, hidden tumors that standard scans miss. About 100 pa…
Sponsor: Boston Scientific Corporation • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
-
Massive pancreatic surgery registry launches to improve patient care
Knowledge-focused OngoingThis registry collects information from 2000 people who have had pancreatic surgery for benign or malignant tumors. Researchers track complications and long-term results to understand what works best. The goal is to improve quality of care and support future research.
Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
-
120,000-Person study hopes to crack the code of chronic illness
Knowledge-focused PausedThis observational study plans to enroll 120,000 people with various chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will collect blood samples and health data to study how genetics and lifestyle affect disease progression. The goal is to find common dise…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC