Overnutrition

This study tests two experimental drugs, PF-08653945 and PF-08653944, given alone or together, for weight loss in adults with overweight or obesity. About 872 participants will receive either the drugs or a placebo injection. The main goal is to see how much weight they lose over…

This Phase 3 trial tests a new medicine called MET097, given as a weekly injection, to help adults with overweight or obesity and type 2 diabetes lose weight. About 999 people will take part, with two-thirds getting the real drug and one-third getting a placebo. The study lasts a…

This phase 2 trial tests different doses of tirzepatide in 414 adults with type 2 diabetes and obesity who already take metformin. The goal is to see if the drug helps with weight loss and blood sugar control. Participants receive either tirzepatide or a placebo for about 89 week…

This trial tests a combined nutrition education package for mothers of children under five in Debre Berhan, Ethiopia. The program promotes dietary diversity, limits high-energy foods, and guides food choices to address undernutrition and overnutrition at the same time. Researcher…

This study tests whether coaching for Latino mothers on how to feed and put their babies to sleep can prevent obesity in the first two years of life. About 256 mothers and their healthy full-term infants will receive either group coaching or text-based support. The goal is to hel…

Researchers are studying whether a mother's weight and blood sugar during pregnancy affect the makeup of her breast milk, and whether those differences influence how her baby grows. The study will follow pregnant women with a range of body sizes, including those with gestational …

This study tests whether Eatable Alphabet cards—a fun, child-friendly nutrition tool—can help kids ages 2 to 10 with overweight or obesity eat more fruits and vegetables. About 160 children in a weight management program will use the cards, and parents will report changes in thei…