Ovarian hyperstimulation syndrome
MONDO:0011972A complication of ovulation induction in infertility treatment. It is graded by the severity of symptoms which include ovary enlargement, multiple ovarian follicles; ovarian cysts; ascites; and generalized edema. The full-blown syndrome may lead to renal failure, respiratory distress, and even death. Increased capillary permeability is caused by the vasoactive substances, such as vascular endothelial growth factors, secreted by the overly-stimulated ovaries.
Also known as: OHSS, ovarian hyperstimulation syndrome, ovarian hyperstimulation syndrome, familial gestational spontaneous
12 clinical trials for this condition and its sub-types, 12 tagged with Ovarian hyperstimulation syndrome itself.
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Can a simple supplement boost IVF success in PCOS?
Disease control CompletedThis trial tests whether myo-inositol, a natural supplement, can improve fertility treatment outcomes in women with polycystic ovary syndrome (PCOS). Participants take myo-inositol with folic acid or folic acid alone for three months before IVF or ICSI. The study measures egg qua…
Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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IVF showdown: which drug combo gives more usable embryos?
Disease control CompletedThis study looked at 846 women doing their first IVF cycle to compare two drug mixes: follitropin delta plus menotropin versus follitropin alfa plus menotropin. The goal was to see which combination leads to more usable embryos and lower costs. Results help doctors choose the mos…
Sponsor: Clinique Ovo • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New drug combo may prevent dangerous ovarian condition in fertility patients
Prevention CompletedThis study tested whether giving albumin and furosemide right after egg retrieval can prevent severe ovarian hyperstimulation syndrome (OHSS) in women at high risk during ICSI. OHSS can cause swelling, fluid buildup, and sometimes hospitalization. The trial involved 200 women and…
Sponsor: Al-Nahrain University • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
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New study tests drug to ease pain during fertility treatment for endometriosis patients
Symptom relief CompletedThis phase 2 trial tested whether the drug letrozole can reduce pain during ovarian stimulation in 60 women with endometriosis. Participants received either letrozole or a placebo daily, and researchers measured changes in pain scores. The goal is to find a way to make fertility …
Phase 2 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Fertility hormone absorption measured in healthy women
Knowledge-focused CompletedThis study looked at how two fertility hormones, FSH and hCG, are absorbed after daily injections in 28 healthy women. The goal was to understand the drug's behavior in the body, not to treat infertility directly. Results will help design better ovarian stimulation treatments for…
Phase 1 • Sponsor: IBSA Institut Biochimique SA • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Fertility drug levels measured in healthy women
Knowledge-focused CompletedThis study looked at how a single injection of Gonadotropins-IBSA, a fertility drug, is processed by the body. It involved 29 healthy women of childbearing age. The goal was to measure hormone levels and check for side effects, not to treat infertility directly.
Phase 1 • Sponsor: IBSA Institut Biochimique SA • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC