Ovarian dysfunction
MONDO:0001889The inability of the ovaries to function.
Also known as: ovarian failure, ovarian hypofunction, ovarian insufficiency
119 clinical trials for this condition and its sub-types, 27 tagged with Ovarian dysfunction itself.
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Sub-types of Ovarian dysfunction
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Primary ovarian failure 53 trials · 103 incl. sub-types
4 sub-types
- Inherited primary ovarian failure 2 trials · 47 incl. sub-types Sub-types →
- Premature menopause 22 trials
- Acquired primary ovarian failure 1 trial
- Autoimmune primary ovarian failure 1 trial
Most studied deeper sub-types
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Herbal hope: TCM trial targets fertility in women with low egg reserve
Disease control Recruiting nowThis study tests a traditional Chinese medicine called Yulinzhu in 60 women aged 18-40 with diminished ovarian reserve (low egg supply). Participants take the herbal therapy for 12 weeks, and researchers measure changes in hormone levels and egg count. The goal is to see if the t…
Phase 3 • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Could a shot of your own blood help your ovaries produce more eggs?
Disease control Recruiting nowThis trial investigates whether infusing a woman's own platelet-rich plasma (PRP) into her ovaries can improve egg production and hormone levels in those with poor ovarian response to fertility treatments. The study involves 100 women who have had difficulty producing enough eggs…
Phase 2/3 • Sponsor: Genesis Athens Clinic • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Herbal hope for ovarian health: new trial tests ancient remedy
Disease control Recruiting nowThis study tests whether a traditional Chinese herbal formula (Bu Shen Yi Qi) combined with the hormone DHEA can improve ovarian function in women with diminished ovarian reserve. 74 women aged 20-40 will receive either the herbal formula plus DHEA or a placebo plus DHEA for 12 w…
Phase 1/2 • Sponsor: Jiangxi University of Traditional Chinese Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Can light and herbs boost ovarian function? new trial seeks answers
Disease control Recruiting nowThis study tests whether a combination of light therapy on acupoints and a traditional Chinese medicine pill can improve ovarian function in women with diminished ovarian reserve (DOR). Ninety women aged 25-40 will be split into three groups: light plus placebo, light plus Chines…
Phase 3 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New hormone protocol could make IVF cheaper and easier for women with low egg supply
Disease control Recruiting nowThis study tests whether using the hormone dydrogesterone (taken as a pill) alongside standard fertility injections can help women with low ovarian reserve collect more eggs for IVF. The trial compares this approach to the usual GnRH antagonist protocol. Researchers will track pr…
Sponsor: Tam Anh TP. Ho Chi Minh General Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Royal jelly supplement tested for boosting fertility in women
Disease control Recruiting nowThis study tests whether a dietary supplement made from royal jelly (MRJPs) can improve ovarian function and the thickness of the uterine lining in women with diminished ovarian reserve or thin endometrium. Sixty-six women aged 20 to 45 will take either the supplement or a placeb…
Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Frozen ovary transplant could help cancer survivors have babies
Disease control Recruiting nowThis study tests whether transplanting a woman's own frozen ovarian tissue can restore fertility after cancer treatment. Ten women who became infertile due to chemotherapy or radiation will receive the transplant. The goal is to see if they can get pregnant and have normal menstr…
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 26, 2026 16:19 UTC
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New study creates ovarian tissue databank to unlock fertility secrets
Knowledge-focused Recruiting nowThis study collects and stores ovarian tissue from females aged 4 to 35 who choose to freeze a sample before cancer treatment that could harm their fertility. Researchers will also gather medical data and annual surveys for up to 30 years. The goal is to build a national database…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can freezing ovarian tissue help people with turner syndrome or early menopause have kids?
Knowledge-focused Recruiting nowThis study looks at whether freezing ovarian tissue can help preserve fertility in people aged 2-21 with conditions like Turner syndrome, galactosemia, or premature ovarian insufficiency. Participants may have surgery to remove and freeze a gonad, with a small piece used for rese…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC