Otorhinolaryngologic disease
MONDO:0024623Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases.
Also known as: ear, nose and throat disorder, ear, nose or throat disorder, ear/nose/throat disease, otolaryngologic disorder, otorhinolaryngologic disease, ENT disease, ENT diseases, disease, ENT
1326 clinical trials for this condition and its sub-types, 15 tagged with Otorhinolaryngologic disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Otorhinolaryngologic disease
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Disorder of pharynx 3 trials · 598 incl. sub-types
10 sub-types
- Pharynx cancer 10 trials · 497 incl. sub-types Sub-types →
- Neoplasm of oropharynx 3 trials · 280 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Neoplasm of hypopharynx 0 trials · 100 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 28 incl. sub-types Sub-types →
- Takayasu arteritis 27 trials
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Epiglottitis 1 trial Sub-types →
- Oropharyngeal anthrax 0 trials
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Nasal disorder 3 trials · 375 incl. sub-types
5 sub-types
- Nasal cavity disorder 3 trials · 226 incl. sub-types Sub-types →
- Paranasal sinus disorder 12 trials · 163 incl. sub-types Sub-types →
- Anosmia 35 trials Sub-types →
- Nasal cavity and paranasal sinus lethal midline granuloma 0 trials
- Nasal dermoid cyst 0 trials
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Disorder of ear 8 trials · 254 incl. sub-types
6 sub-types
- Inner ear disorder 8 trials · 149 incl. sub-types Sub-types →
- Middle ear disorder 3 trials · 75 incl. sub-types Sub-types →
- Ear infection 9 trials · 40 incl. sub-types Sub-types →
- External ear disorder 0 trials · 13 incl. sub-types Sub-types →
- Hyperacusis 10 trials Sub-types →
- Ear neoplasm 0 trials · 3 incl. sub-types Sub-types →
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Lip and oral cavity squamous cell carcinoma 21 trials · 159 incl. sub-types
1 sub-type
- Oral cavity squamous cell carcinoma 141 trials · 156 incl. sub-types Sub-types →
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Hereditary otorhinolaryngologic disease 0 trials · 102 incl. sub-types
21 sub-types
- X-linked mixed hearing loss with perilymphatic gusher 32 trials
- Benign paroxysmal positional vertigo 18 trials
- Meniere disease 16 trials Sub-types →
- Motion sickness 14 trials · 16 incl. sub-types Sub-types →
- Familial congenital nasolacrimal duct obstruction 7 trials
- Choanal atresia 4 trials Sub-types →
- Otosclerosis 4 trials Sub-types →
- Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome 2 trials
- Familial thyroglossal duct cyst 2 trials
- BNAR syndrome 1 trial
- Aural atresia, congenital 1 trial
- Second branchial cleft anomaly 1 trial
- Short stature-auditory canal atresia-mandibular hypoplasia-skeletal anomalies syndrome 1 trial
- X-linked external auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome 0 trials
- Bifid nose, autosomal recessive 0 trials Sub-types →
- Familial nasal acilia 0 trials
- Isolated congenital anosmia 0 trials
- Nasal dermoid cyst 0 trials
- Tonsillar lymphoma 0 trials
- Tympanic paraganglioma 0 trials
- Vertigo, benign recurrent, 1 0 trials
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Idiopathic bilateral vestibulopathy 14 trials
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Laryngeal abductor paralysis 10 trials
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Recurrent respiratory papillomatosis 8 trials · 9 incl. sub-types
1 sub-type
- Laryngeal papillomatosis 1 trial
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Microtia 8 trials
1 sub-type
- Ear without helix 0 trials
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Congenital tracheomalacia 6 trials
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Autoimmune disease of ear, nose and throat 0 trials · 4 incl. sub-types
7 sub-types
- Autoimmune inner ear disease 2 trials
- Autoimmune uveitis 2 trials
- Cogan syndrome 0 trials
- IgG4-related dacryoadenitis and sialadenitis 0 trials
- IgG4-related submandibular gland disease 0 trials
- Autoimmune retinopathy 0 trials
- Eosinophilic angiocentric fibrosis 0 trials
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Cysts and fistulae of the face and oral cavity 0 trials · 3 incl. sub-types
13 sub-types
- Familial thyroglossal duct cyst 2 trials
- First branchial cleft anomaly 1 trial
- Second branchial cleft anomaly 1 trial
- Cervical dermoid cyst 0 trials
- Cervicofacial fibrochondroma 0 trials
- Commissural lip fistula 0 trials
- Digestive duplication cyst of the tongue 0 trials
- Facial dermoid cyst 0 trials Sub-types →
- Fourth branchial cleft anomaly 0 trials
- Lower lip fistula 0 trials
- Nasal dorsum fistula/cyst 0 trials
- Pinnae fistula or cyst 0 trials
- Third branchial cleft anomaly 0 trials
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Mal de Debarquement 2 trials
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Anotia 1 trial
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Bifid nose 0 trials · 1 incl. sub-types
3 sub-types
- BNAR syndrome 1 trial
- Bifid nose, autosomal dominant 0 trials
- Bifid nose, autosomal recessive 0 trials Sub-types →
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Arrhinia 0 trials
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Congenital tracheal stenosis 0 trials
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Epignathus 0 trials
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Isolated congenital syngnathia 0 trials
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Laryngeal neuroendocrine neoplasm 0 trials
1 sub-type
- Laryngeal small cell carcinoma 0 trials
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Laryngotracheal angioma 0 trials
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Larynx atresia 0 trials
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Middle ear anomaly 0 trials
3 sub-types
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Nasal encephalocele 0 trials
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Nasal ganglioglioma 0 trials
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Nasal glial heterotopia 0 trials
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Nasolacrimal duct cyst 0 trials
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Polyrrhinia 0 trials
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Proboscis lateralis 0 trials
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Silent sinus syndrome 0 trials
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Supernumerary nostril 0 trials
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Supratip dysplasia 0 trials
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Tracheal agenesis 0 trials
Most studied deeper sub-types
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Could less be more? trial tests reduced radiation and chemo after surgery for HPV-Linked throat cancer
Disease control Recruiting nowThis trial studies people with HPV-positive oropharynx cancer whose tumors can be surgically removed. After surgery, patients are grouped by risk: low-risk patients get no further treatment, intermediate-risk get a lower dose of radiation, and high-risk get lower-dose radiation p…
Phase 2 • Sponsor: Heath Skinner • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Tailored surgery may help kids with sleep apnea and small tonsils
Disease control Recruiting nowThis study compares a personalized surgical approach using sleep endoscopy to standard tonsil removal in 240 children aged 2-17 with small tonsils and moderate-to-severe obstructive sleep apnea. The goal is to see if tailoring surgery to each child's specific airway blockages imp…
Sponsor: Oregon Health and Science University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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New nasal numbing sprays tested in teens for Pain-Free nose surgeries
Symptom relief Recruiting nowThis study tests two nasal sprays, GOPRELTO and NUMBRINO, that numb the nose for procedures like surgery or exams. It involves 40 teens aged 12 to 17. Researchers will measure how the drug moves through the body and check for side effects.
Phase 3 • Sponsor: Noden Pharma • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Massive device registry aims to improve patient safety
Knowledge-focused Recruiting nowThis study is a registry that collects information on the safety and effectiveness of Medtronic medical devices already on the market. It will include up to 100,000 people who have or will receive a Medtronic product for conditions like heart, nerve, or digestive disorders. The g…
Sponsor: Medtronic • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Scientists gather data to unlock secrets of hearing and balance
Knowledge-focused Recruiting nowThis study collects medical information and samples from people with hearing, balance, taste, smell, voice, speech, or language disorders. Researchers aim to use this data for future studies and to find candidates for other research. Participants receive standard care, and no exp…
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC