Nutritional deficiency disease
MONDO:0006873A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)
Also known as: malnourished, malnutrition
508 clinical trials for this condition and its sub-types, 235 tagged with Nutritional deficiency disease itself.
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Sub-types of Nutritional deficiency disease
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Vitamin deficiency disorder 9 trials · 135 incl. sub-types
8 sub-types
- Vitamin D deficiency 89 trials
- Vitamin B deficiency 0 trials · 17 incl. sub-types Sub-types →
- Scurvy 13 trials
- Vitamin A deficiency 9 trials
- Inborn vitamin metabolic disorder 0 trials · 7 incl. sub-types Sub-types →
- Vitamin K deficiency hemorrhagic disease 2 trials
- Nutritional biotin deficiency 0 trials
- Vitamin deficiency related neuropathy 0 trials
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Iron deficiency anemia 123 trials
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Protein-energy malnutrition 34 trials
2 sub-types
- Kwashiorkor 7 trials
- Marasmus 1 trial
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Folic acid deficiency anemia 5 trials
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Magnesium deficiency 5 trials
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Endemic goiter 4 trials
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Wernicke-Korsakoff syndrome 1 trial
1 sub-type
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Choline deficiency disease 1 trial
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Pernicious anemia 1 trial
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Potassium deficiency 1 trial
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Keshan disease 0 trials
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Acquired night blindness 0 trials
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Ariboflavinosis 0 trials
1 sub-type
- Maternal riboflavin deficiency 0 trials
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Pellagra 0 trials
Most studied deeper sub-types
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Iron infusions put to the test for heart failure stamina
Disease control Stopped earlyThis trial tests whether a single intravenous iron infusion can improve exercise capacity in people with heart failure and iron deficiency. Participants are randomly assigned to receive the infusion or no treatment, then undergo cardiopulmonary exercise testing to measure peak ox…
Phase 4 • Sponsor: Radha Gopalan • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Iron showdown: IV vs. pills for heart failure fatigue
Disease control Stopped earlyThis trial tests whether intravenous (IV) iron or oral iron pills work better for adults with congestive heart failure who also have low iron levels. Participants are randomly assigned to receive either a one-time IV infusion of ferric carboxymaltose (with a possible repeat dose)…
Phase 4 • Sponsor: Syed Hamza Mufarrih • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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New vitamin d pill aims to tame parathyroid glands in dialysis patients
Disease control Stopped earlyThis phase 2 study tested a weekly extended-release capsule of calcifediol (CTAP101) in 44 adults with chronic kidney disease on hemodialysis who also had vitamin D insufficiency and secondary hyperparathyroidism. The goal was to see if the drug could raise vitamin D levels and l…
Phase 2 • Sponsor: OPKO Health, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Could a vitamin d boost make flu shots work better for seniors?
Prevention Stopped earlyThis trial tests whether giving older adults a high dose of vitamin D before their flu shot can strengthen their immune response. Participants are 65 or older with low vitamin D levels. The study measures changes in infection-fighting proteins and antibody levels after vaccinatio…
Phase 2 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Prevention
Last updated Aug 08, 2026 00:03 UTC
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Two eggs a day for healthier babies? new study tests simple fix for malnutrition
Prevention Stopped earlyThis study tests whether pregnant women who eat two eggs daily have babies with longer birth lengths and better development. Researchers in Rwanda are giving eggs to some women and comparing them to those eating their usual diet. The goal is to see if this simple, affordable food…
Sponsor: University of Florida • Aim: Prevention
Last updated Jul 08, 2026 00:00 UTC
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New tube feeding formula aims to ease digestive troubles
Symptom relief Stopped earlyThis study looked at whether switching to a high-energy, high-protein tube feeding formula (Sondalis HP 2 kcal) improves digestive comfort and quality of life in adults who have trouble tolerating their current home tube feeding. Seventeen adults on home enteral nutrition took th…
Sponsor: Société des Produits Nestlé (SPN) • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC