Nodular goiter
MONDO:0006869Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.
Also known as: goiter, nodular, nodular goiter, nodular goiter (disease), nodular goitre (disease), nodular goitre NOS
43 clinical trials for this condition and its sub-types, 36 tagged with Nodular goiter itself.
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Sub-types of Nodular goiter
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Multinodular goiter 10 trials
3 sub-types
- Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors 1 trial
- Goiter, multinodular 2 0 trials
- Goiter, multinodular 3 0 trials
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New procedure shrinks giant goiters without surgery
Disease control By invitation onlyThis study tests a new, less invasive treatment for large thyroid nodules (giant nodular goiter) that cause discomfort or breathing problems. The procedure uses a tiny tube to deliver a chemotherapy drug (bleomycin) directly into the nodule's blood supply, blocking it and shrinki…
Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New registry to see if blocking thyroid blood flow improves symptoms
Disease control By invitation onlyThis registry study follows 100 adults who have had a procedure called thyroid embolization to treat hyperthyroidism, goiter, or thyroid nodules. The procedure uses a catheter to block blood flow to the thyroid, aiming to shrink it and reduce symptoms. Researchers will track chan…
Sponsor: Sarasota Memorial Health Care System • Aim: Disease control
Last updated Jun 26, 2026 14:53 UTC
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Urine test may spot hidden thyroid cancer, avoid unnecessary surgery
Diagnosis OngoingThis study looks at whether proteins found in urine can help doctors diagnose follicular thyroid cancer before surgery. Currently, this type of thyroid cancer can only be confirmed after removing the thyroid. Researchers will collect urine samples from 50 patients with thyroid no…
Sponsor: National Taiwan University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Heat zaps thyroid lumps without surgery
Symptom relief OngoingThis study tests if a single session of radiofrequency ablation (using heat) can safely shrink benign (non-cancerous) thyroid nodules in 106 adults. The goal is to reduce symptoms like neck pressure or cosmetic concerns. Participants will be followed for a year to measure nodule …
Sponsor: Hue University of Medicine and Pharmacy • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New 3D ultrasound aims to sharpen thyroid nodule measurements
Knowledge-focused By invitation onlyThis study compares a new 3D ultrasound technology (PIUR) with standard 2D ultrasound for measuring thyroid nodule size after ablation. Researchers want to see if the 3D method gives more accurate and consistent results. About 75 adults who are having thyroid nodule ablation will…
Sponsor: Sarasota Memorial Health Care System • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:57 UTC