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Heat zaps thyroid lumps without surgery

NCT ID NCT07115576

Symptom relief Sponsor: Hue University of Medicine and Pharmacy Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if a single session of radiofrequency ablation (using heat) can safely shrink benign (non-cancerous) thyroid nodules in 106 adults. The goal is to reduce symptoms like neck pressure or cosmetic concerns. Participants will be followed for a year to measure nodule shrinkage and check for side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 106 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2023

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with thyroid nodules, confirmed by ultrasound. * Presence of compressive symptoms (e.g., dysphagia, neck pressure) or cosmetic concerns. * Documented thyroid function tests (serum free thyroxine \[FT4\] and thyrotropin \[TSH\]). * Cytology-confirmed benign thyroid nodules via one or two ultrasound-guided fine-needle aspiration (FNA) procedures. * Refusal of surgical treatment. * Ability to complete follow-up assessments at 1, 6, and 12 months post-procedure. Exclusion Criteria: * Malignant or indeterminate cytology on FNA. * Contraindications to RFA (e.g., severe coagulopathy, pregnancy). * Uncontrolled thyroid dysfunction (e.g., hyperthyroidism or hypothyroidism). * Inability to provide informed consent or comply with follow-up

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm nodular goiter

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Benign thyroid nodules

Contacts and locations

Locations

  • Hue University of Medicine and Pharmacy, Hue University,

    Huế, 49000, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.