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Neurodevelopmental disorder
MONDO:0700092A behavioral and cognitive disorder with onset during the developmental period that involves impaired or aberrant development of intellectual, motor, or social functions.
1128 clinical trials for this condition and its sub-types, 161 tagged with Neurodevelopmental disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Neurodevelopmental disorder
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Complex neurodevelopmental disorder 3 trials · 871 incl. sub-types
15 sub-types
- Pervasive developmental disorder 21 trials · 737 incl. sub-types Sub-types →
- Developmental and epileptic encephalopathy 29 trials · 98 incl. sub-types Sub-types →
- Prader-Willi syndrome 31 trials Sub-types →
- Complex neurodevelopmental disorder with motor features 1 trial · 10 incl. sub-types Sub-types →
- GRIN-related complex neurodevelopmental disorder 2 trials Sub-types →
- AFG2B-related complex neurodevelopmental disorder with motor features and hearing loss 0 trials
- DEAF1-associated neurodevelopmental disorder 0 trials Sub-types →
- NACC1-related neurodevelopmental disorder with epilepsy, cataracts and episodic irritability 0 trials
- X-linked complex neurodevelopmental disorder 0 trials Sub-types →
- Complex neurodevelopmental disorder with or without congenital anomalies 0 trials Sub-types →
- Intellectual disability, autosomal dominant 29 0 trials
- Neonatal encephalopathy with non-epileptic myoclonus 0 trials
- Neurodevelopmental disorder with language impairment and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with severe motor impairment and absent language 0 trials
- Syndromic complex neurodevelopmental disorder 0 trials Sub-types →
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Mendelian neurodevelopmental disorder 0 trials · 207 incl. sub-types
275 sub-types
- Genetic developmental and epileptic encephalopathy 2 trials · 83 incl. sub-types Sub-types →
- Prader-Willi syndrome 31 trials Sub-types →
- Rett syndrome 31 trials
- Intellectual disability, autosomal dominant 0 trials · 23 incl. sub-types Sub-types →
- X-linked intellectual disability 1 trial · 15 incl. sub-types Sub-types →
- CACNA1A-related complex neurodevelopmental disorder 1 trial · 9 incl. sub-types Sub-types →
- Autosomal recessive primary microcephaly 0 trials · 8 incl. sub-types Sub-types →
- Smith-Magenis syndrome 5 trials
- Rubinstein-Taybi syndrome 3 trials Sub-types →
- Alternating hemiplegia of childhood 3 trials Sub-types →
- FOXG1 disorder 2 trials
- GRIN-related complex neurodevelopmental disorder 2 trials Sub-types →
- Neurodevelopmental disorder with involuntary movements 2 trials
- CAMK2D-related neurodevelopmental disorder and dilated cardiomyopathy 1 trial
- Dyneinopathy 0 trials · 1 incl. sub-types Sub-types →
- Intellectual disability, autosomal recessive 0 trials · 1 incl. sub-types Sub-types →
- Microcephalic osteodysplastic primordial dwarfism type I 1 trial
- Microcephalic osteodysplastic primordial dwarfism type II 1 trial
- Neurodevelopmental disorder with cerebellar atrophy and motor dysfunction 1 trial
- Neurodevelopmental disorder with or without variable brain abnormalities; NEDBA 1 trial
- Orofaciodigital syndrome I 1 trial
- AFG2B-related complex neurodevelopmental disorder with motor features and hearing loss 0 trials
- AHDC1-related intellectual disability - obstructive sleep apnea - mild dysmorphism syndrome 0 trials
- ARF3-related neurodevelopmental disorder 0 trials
- ATXN7L3-related developmental delay, hypotonia and facial dysmorphism 0 trials
- Alzahrani-Kuwahara syndrome 0 trials
- Amish lethal microcephaly 0 trials
- Au-Kline syndrome 0 trials
- Brunet-Wagner neurodevelopmental syndrome 0 trials
- CBX1-related neurodevelopmental disorder 0 trials
- CK syndrome 0 trials
- CNOT9-related developmental disorder with seizures 0 trials
- CTR9-related neurodevelopmental disorder 0 trials
- Chilton-Okur-Chung neurodevelopmental syndrome 0 trials
- DDX17-related neurodevelopmental disorder 0 trials
- DEAF1-associated neurodevelopmental disorder 0 trials Sub-types →
- DIP2C-related developmental disorder with speech delay 0 trials
- Delpire-McNeill syndrome 0 trials
- Dentici-Novelli neurodevelopmental syndrome 0 trials
- Dursun-Ozgul neurodevelopmental syndrome 0 trials
- Dworschak-Punetha neurodevelopmental syndrome 0 trials
- EPB41L3-related developmental disorder with delayed myelination and seizures 0 trials
- El Hayek-Chahrour neurodevelopmental disorder 0 trials
- FAT4-related neurodevelopmental disorder 0 trials
- FEZF2-related neurodevelopmental disorder 0 trials
- Ferguson-Bonni neurodevelopmental syndrome 0 trials
- GABRA4-related neurodevelopmental disorder with seizures 0 trials
- GABRD-related neurodevelopmental disorder with epilepsy 0 trials
- HDAC3-related neurodevelopmental disorder 0 trials
- HMGB1-related brachyphalangy, polydactyly and tibial aplasia syndrome 0 trials
- HNRNPC-related neurodevelopmental disorder 0 trials Sub-types →
- Hao-Fountain syndrome due to USP7 mutation 0 trials
- Harel-Tora neurodevelopmental syndrome 0 trials
- Harel-Yoon syndrome 0 trials
- Hiatt-Neu-Cooper neurodevelopmental syndrome 0 trials
- Houge-Janssens syndrome 3 0 trials
- Jeffries-Lakhani neurodevelopmental syndrome 0 trials
- KCND2-related neurodevelopmental disorder with or without seizures 0 trials
- KCNH1 associated disorder 0 trials Sub-types →
- KCNK3-related developmental delay with sleep apnea 0 trials
- KDM2B-related neurodevelopmental disorder 0 trials
- Karayol-Borroto-Haghshenas neurodevelopmental syndrome 0 trials
- Kariminejad neurodevelopmental syndrome 0 trials
- Li-Takada-Miyake syndrome 0 trials
- MYCBP2-related developmental delay with corpus callosum defects 0 trials
- MYH10-related neurodevelopmental disorder with congenital anomalies 0 trials
- Marbach-Schaaf neurodevelopmental syndrome 0 trials
- NACC1-related neurodevelopmental disorder with epilepsy, cataracts and episodic irritability 0 trials
- Nil-Deshwar neurodevelopmental syndrome 0 trials
- Okur-Chung neurodevelopmental syndrome 0 trials
- PAX5-related B lymphopenia and autism spectrum disorder 0 trials
- PIP5K1C-related neurodevelopmental disorder 0 trials
- PPFIA3-related neurodevelopmental disorder 0 trials
- PPP2R1A-related intellectual disability 0 trials
- PRPF19-related neurodevelopmental disorder 0 trials
- Pitt-Hopkins-like syndrome 2 0 trials
- Poirier-Bienvenu neurodevelopmental syndrome 0 trials
- Popov-Chang syndrome 0 trials
- RFX3-related neurodevelopmental disorder with autism and other behavioural abnormalities 0 trials
- RFX4-related neurodevelopmental disorder with autism and other behavioural abnormalities 0 trials
- RNU5B-1 related neurodevelopmental disorder with seizures and joint laxity 0 trials
- Ramond-Elliott neurodevelopmental syndrome 0 trials
- SETD2-related neurodevelopmental disorder without or with macrocephaly/overgrowth 0 trials Sub-types →
- SOX11-related complex neurodevelopmental disorder with or without congenital anomalies 0 trials
- SYNCRIP-related neurodevelopmental disorder 0 trials
- Stankiewicz-Isidor syndrome 0 trials
- TRA2B-related neurodevelopmental disorder 0 trials
- WDR5-related neurodevelopmental disorder 0 trials
- Wieacker-Wolff syndrome 0 trials
- X-linked complex neurodevelopmental disorder 0 trials Sub-types →
- Aplasia cutis-enamel dysplasia syndrome 0 trials
- Autosomal dominant primary microcephaly 0 trials Sub-types →
- Cerebellar atrophy, visual impairment, and psychomotor retardation; 0 trials
- Cerebral palsy, spastic quadriplegic, 2 0 trials
- Cerebral palsy, spastic quadriplegic, 3 0 trials
- Complex cortical dysplasia with other brain malformations 5 0 trials
- Developmental delay and seizures with or without movement abnormalities 0 trials
- Developmental delay with autism spectrum disorder and gait instability 0 trials
- Developmental delay with variable intellectual impairment and behavioral abnormalities 0 trials
- Encephalopathy, neonatal severe, with lactic acidosis and brain abnormalities 0 trials
- Intellectual developmental disorder and retinitis pigmentosa; IDDRP 0 trials
- Intellectual developmental disorder with polymicrogyria and seizures 0 trials
- Intellectual disability, autosomal dominant 29 0 trials
- Microcephalic osteodysplastic primordial dwarfism, type 3 0 trials
- Microcephaly and chorioretinopathy 0 trials Sub-types →
- Microcephaly with lissencephaly and/or hydranencephaly 0 trials Sub-types →
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Microcephaly, progressive, with simplified gyral pattern and cerebellar hypoplasia 0 trials
- Neurocardiorenal malformation syndrome 0 trials
- Neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity 0 trials
- Neurodevelopmental disorder plus optic atrophy 0 trials
- Neurodevelopmental disorder with absent language and variable seizures 0 trials
- Neurodevelopmental disorder with absent speech and movement and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with achalasia, polyneuropathy, and alacrima 0 trials
- Neurodevelopmental disorder with alopecia and brain abnormalities 0 trials
- Neurodevelopmental disorder with ataxia and brain abnormalities 0 trials
- Neurodevelopmental disorder with ataxia, hypotonia, and microcephaly 0 trials
- Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter 0 trials
- Neurodevelopmental disorder with behavioral abnormalities and childhood-onset spastic paraplegia 0 trials
- Neurodevelopmental disorder with behavioral abnormalities, absent speech, and hypotonia 0 trials
- Neurodevelopmental disorder with behavioral, ear, and skeletal abnormalities 0 trials
- Neurodevelopmental disorder with brain anomalies and with or without vertebral or cardiac anomalies 0 trials
- Neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities 0 trials
- Neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies 0 trials
- Neurodevelopmental disorder with central and peripheral motor dysfunction 0 trials
- Neurodevelopmental disorder with central hypotonia and dysmorphic facies 0 trials Sub-types →
- Neurodevelopmental disorder with cerebellar atrophy and with or without seizures 0 trials
- Neurodevelopmental disorder with cerebellar hypoplasia and spasticity 0 trials
- Neurodevelopmental disorder with cerebral atrophy and variable facial dysmorphism 0 trials
- Neurodevelopmental disorder with characteristic facial and ectodermal features and tetraparesis 1 0 trials
- Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities 0 trials
- Neurodevelopmental disorder with congenital cardiac defects and variable renal and ocular abnormalities 0 trials
- Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects 0 trials
- Neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with dysmorphic facies and cerebellar hypoplasia 0 trials
- Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies 0 trials
- Neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies 0 trials
- Neurodevelopmental disorder with dysmorphic facies and ischiopubic hypoplasia 0 trials
- Neurodevelopmental disorder with dysmorphic facies and skeletal and brain abnormalities 0 trials
- Neurodevelopmental disorder with dysmorphic facies and thin corpus callosum 0 trials
- Neurodevelopmental disorder with dysmorphic facies and variable seizures 0 trials
- Neurodevelopmental disorder with dysmorphic facies, absent speech and ambulation, and brain abnormalities 0 trials
- Neurodevelopmental disorder with dysmorphic facies, brain anomalies, and seizures 0 trials
- Neurodevelopmental disorder with dysmorphic facies, impaired speech, and hypotonia 0 trials
- Neurodevelopmental disorder with dysmorphic facies, sleep disturbance, and brain abnormalities 0 trials
- Neurodevelopmental disorder with dystonia and seizures 0 trials
- Neurodevelopmental disorder with early-onset parkinsonism and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with early-onset seizures, facial dysmorphism, and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with epilepsy and brain atrophy 0 trials
- Neurodevelopmental disorder with epilepsy and hypoplasia of the corpus callosum 0 trials
- Neurodevelopmental disorder with epilepsy, cataracts, feeding difficulties, and delayed brain myelination 0 trials
- Neurodevelopmental disorder with epilepsy, spasticity, and brain atrophy 0 trials
- Neurodevelopmental disorder with eye movement abnormalities and ataxia 0 trials
- Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly 0 trials
- Neurodevelopmental disorder with gait disturbance, dysmorphic facies, and behavioral abnormalities, X-linked 0 trials
- Neurodevelopmental disorder with growth impairment, quadriparesis, and poor or absent speech 0 trials
- Neurodevelopmental disorder with growth retardation, dysmorphic facies, and corpus callosum abnormalities 0 trials
- Neurodevelopmental disorder with hearing loss and spasticity 0 trials
- Neurodevelopmental disorder with hyperkinetic movements and dyskinesia 0 trials
- Neurodevelopmental disorder with hyperkinetic movements, seizures, and structural brain abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements 0 trials
- Neurodevelopmental disorder with hypotonia and brain abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia and cerebellar atrophy, with or without seizures 0 trials
- Neurodevelopmental disorder with hypotonia and characteristic brain abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia and dysmorphic facies 0 trials
- Neurodevelopmental disorder with hypotonia and gross motor and speech delay 0 trials
- Neurodevelopmental disorder with hypotonia and seizures 0 trials
- Neurodevelopmental disorder with hypotonia and speech delay, with or without seizures 0 trials
- Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia, brain anomalies, distinctive facies, and absent language 0 trials
- Neurodevelopmental disorder with hypotonia, dysmorphic facies, and skeletal anomalies, with or without seizures 0 trials
- Neurodevelopmental disorder with hypotonia, dysmorphic facies, and skin abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia, epilepsy, and absent speech 0 trials
- Neurodevelopmental disorder with hypotonia, facial dysmorphism, and brain abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia, feeding difficulties, facial dysmorphism, and brain abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures 0 trials
- Neurodevelopmental disorder with hypotonia, microcephaly, and seizures 0 trials
- Neurodevelopmental disorder with hypotonia, neonatal respiratory insufficiency, and thermodysregulation 0 trials
- Neurodevelopmental disorder with hypotonia, neuropathy, and deafness 0 trials
- Neurodevelopmental disorder with hypotonia, poor growth, dysmorphic facies, and agammaglobulinemia 0 trials
- Neurodevelopmental disorder with hypotonia, seizures, and absent language 0 trials
- Neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia 0 trials
- Neurodevelopmental disorder with impaired language and ataxia and with or without seizures 0 trials
- Neurodevelopmental disorder with impaired language, behavioral abnormalities, and dysmorphic facies 0 trials
- Neurodevelopmental disorder with impaired speech and hyperkinetic movements 0 trials
- Neurodevelopmental disorder with infantile epileptic spasms 0 trials
- Neurodevelopmental disorder with intention tremor, pyramidal signs, dyspraxia, and ocular anomalies 0 trials
- Neurodevelopmental disorder with intracranial hemorrhage, seizures, and spasticity 0 trials
- Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures 0 trials
- Neurodevelopmental disorder with language delay and seizures 0 trials
- Neurodevelopmental disorder with language delay and variable cognitive abnormalities 0 trials
- Neurodevelopmental disorder with language impairment and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with language impairment, autism, and attention deficit-hyperactivity disorder 0 trials
- Neurodevelopmental disorder with microcephaly and dysmorphic facies 0 trials
- Neurodevelopmental disorder with microcephaly and movement abnormalities 0 trials
- Neurodevelopmental disorder with microcephaly and speech delay, with or without brain abnormalities 0 trials
- Neurodevelopmental disorder with microcephaly and structural brain anomalies 0 trials
- Neurodevelopmental disorder with microcephaly, absent speech, and hypotonia 0 trials
- Neurodevelopmental disorder with microcephaly, arthrogryposis, and structural brain anomalies 0 trials
- Neurodevelopmental disorder with microcephaly, ataxia, and seizures 0 trials
- Neurodevelopmental disorder with microcephaly, cataracts, and renal abnormalities 0 trials
- Neurodevelopmental disorder with microcephaly, cerebral atrophy, and visual impairment 0 trials
- Neurodevelopmental disorder with microcephaly, cortical malformations, and spasticity 0 trials
- Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy 0 trials
- Neurodevelopmental disorder with microcephaly, epilepsy, and hypomyelination 0 trials
- Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies 0 trials
- Neurodevelopmental disorder with microcephaly, hypotonia, nystagmus, and seizures 0 trials
- Neurodevelopmental disorder with microcephaly, impaired language, and gait abnormalities 0 trials
- Neurodevelopmental disorder with microcephaly, impaired language, epilepsy, and gait abnormalities 0 trials
- Neurodevelopmental disorder with microcephaly, movement abnormalities, and seizures 0 trials
- Neurodevelopmental disorder with microcephaly, seizures, and brain atrophy 0 trials
- Neurodevelopmental disorder with microcephaly, seizures, and cortical atrophy 0 trials
- Neurodevelopmental disorder with microcephaly, seizures, and neonatal cholestasis 0 trials
- Neurodevelopmental disorder with microcephaly, short stature, and speech delay 0 trials
- Neurodevelopmental disorder with midbrain and hindbrain malformations 0 trials
- Neurodevelopmental disorder with motor abnormalities, seizures, and facial dysmorphism 0 trials
- Neurodevelopmental disorder with motor and language delay, ocular defects, and brain abnormalities 0 trials
- Neurodevelopmental disorder with motor and speech delay and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with motor regression, progressive spastic paraplegia, and oromotor dysfunction 0 trials
- Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features 0 trials
- Neurodevelopmental disorder with neuromuscular and skeletal abnormalities 0 trials
- Neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures 0 trials
- Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart 0 trials
- Neurodevelopmental disorder with or without autism or seizures 0 trials
- Neurodevelopmental disorder with or without autistic features and/or structural brain abnormalities 0 trials
- Neurodevelopmental disorder with or without early-onset generalized epilepsy 0 trials
- Neurodevelopmental disorder with or without seizures and gait abnormalities 0 trials
- Neurodevelopmental disorder with or without variable movement or behavioral abnormalities 0 trials
- Neurodevelopmental disorder with poor growth and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with poor growth and skeletal anomalies 0 trials
- Neurodevelopmental disorder with poor growth, large ears, and dysmorphic facies 0 trials
- Neurodevelopmental disorder with poor growth, seizures, and brain abnormalities 0 trials
- Neurodevelopmental disorder with poor language and loss of hand skills 0 trials
- Neurodevelopmental disorder with poor or absent speech, dysmorphic facies, and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with progressive microcephaly, spasticity, and brain anomalies 0 trials
- Neurodevelopmental disorder with progressive movement abnormalities 0 trials
- Neurodevelopmental disorder with progressive spasticity and brain abnormalities 0 trials
- Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities 0 trials
- Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures 0 trials
- Neurodevelopmental disorder with relative macrocephaly and with or without cardiac or endocrine anomalies 0 trials
- Neurodevelopmental disorder with seizures and brain atrophy 0 trials
- Neurodevelopmental disorder with seizures and gingival overgrowth 0 trials
- Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements 0 trials
- Neurodevelopmental disorder with seizures and speech and walking impairment 0 trials
- Neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities 0 trials
- Neurodevelopmental disorder with seizures, hypotonia, and variable spasticity 0 trials
- Neurodevelopmental disorder with seizures, microcephaly, and brain abnormalities 0 trials
- Neurodevelopmental disorder with seizures, spasticity, and complete or partial agenesis of the corpus callosum 0 trials
- Neurodevelopmental disorder with severe motor impairment and absent language 0 trials
- Neurodevelopmental disorder with severe motor impairment, absent language, cerebral hypomyelination, and brain atrophy 0 trials
- Neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties 0 trials
- Neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures 0 trials
- Neurodevelopmental disorder with spastic quadriplegia, optic atrophy, seizures, and structural brain anomalies 0 trials
- Neurodevelopmental disorder with spasticity and poor growth 0 trials
- Neurodevelopmental disorder with spasticity, cataracts, and cerebellar hypoplasia 0 trials
- Neurodevelopmental disorder with spasticity, seizures, and brain abnormalities 0 trials
- Neurodevelopmental disorder with spasticity, thin corpus callosum, and decreased brain white matter 0 trials
- Neurodevelopmental disorder with speech delay and behavioral abnormalities 0 trials
- Neurodevelopmental disorder with speech delay and variable ocular anomalies 0 trials
- Neurodevelopmental disorder with speech delay, movement abnormalities, and seizures 0 trials
- Neurodevelopmental disorder with speech impairment and dysmorphic facies 0 trials
- Neurodevelopmental disorder with speech impairment and with or without seizures 0 trials
- Neurodevelopmental disorder with speech or visual impairment and brain hypomyelination 0 trials
- Neurodevelopmental disorder with structural brain abnormalities and craniofacial abnormalities 0 trials
- Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies 0 trials
- Neurodevelopmental disorder with thin corpus callosum, hypotonia, and absent language 0 trials
- Neurodevelopmental disorder with variable familial hypercholanemia 0 trials
- Neurodevelopmental disorder with visual defects and brain anomalies 0 trials
- Neurodevelopmental disorder with white matter abnormalities and gait disturbance 0 trials
- Neurodevelopmental disorder, mitochondrial, with abnormal movements and lactic acidosis, with or without seizures 0 trials
- Neurodevelopmental disorder, nonprogressive, with spasticity and transient opisthotonus 0 trials
- Otofacial neurodevelopmental syndrome 0 trials
- Parenti-mignot neurodevelopmental syndrome 0 trials
- Squalene synthase deficiency 0 trials
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Intellectual disability 137 trials · 174 incl. sub-types
10 sub-types
- Syndromic intellectual disability 2 trials · 38 incl. sub-types Sub-types →
- Intellectual disability, autosomal dominant 0 trials · 23 incl. sub-types Sub-types →
- X-linked intellectual disability 1 trial · 15 incl. sub-types Sub-types →
- Non-syndromic intellectual disability 0 trials · 10 incl. sub-types Sub-types →
- Intellectual disability, autosomal recessive 0 trials · 1 incl. sub-types Sub-types →
- NACC1-related neurodevelopmental disorder with epilepsy, cataracts and episodic irritability 0 trials
- PPP2R1A-related intellectual disability 0 trials
- SETD2-related neurodevelopmental disorder without or with macrocephaly/overgrowth 0 trials Sub-types →
- Intellectual developmental disorder and retinitis pigmentosa; IDDRP 0 trials
- Intellectual developmental disorder with polymicrogyria and seizures 0 trials
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Williams syndrome 18 trials
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Microcephaly 4 trials · 13 incl. sub-types
10 sub-types
- Isolated congenital microcephaly 0 trials · 8 incl. sub-types Sub-types →
- Microcephalic osteodysplastic primordial dwarfism 1 trial Sub-types →
- Amish lethal microcephaly 0 trials
- Isolated microcephaly 0 trials
- Microcephaly and chorioretinopathy 0 trials Sub-types →
- Microcephaly with intellectual disability 0 trials Sub-types →
- Microcephaly with lissencephaly and/or hydranencephaly 0 trials Sub-types →
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Microcephaly, progressive, with simplified gyral pattern and cerebellar hypoplasia 0 trials
- Microcephaly, seizures, and developmental delay 0 trials
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Atypical Rett syndrome 0 trials · 12 incl. sub-types
2 sub-types
- Developmental and epileptic encephalopathy, 2 10 trials
- FOXG1 disorder 2 trials
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Alternating hemiplegia 0 trials · 3 incl. sub-types
2 sub-types
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Aicardi syndrome 2 trials
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Hao-Fountain syndrome 0 trials
2 sub-types
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Toluene embryopathy 0 trials
Most studied deeper sub-types
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New hope for dravet syndrome: phase 3 trial of LP352 aims to cut seizure frequency
Disease control OngoingThis study tests whether the drug LP352 can safely reduce seizures in children and adults with Dravet syndrome, a severe form of epilepsy. About 160 participants will receive either LP352 or a placebo, and researchers will track changes in seizure frequency over several months. T…
Phase 3 • Sponsor: Longboard Pharmaceuticals • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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New hope for Hard-to-Treat seizures: phase 3 trial launches
Disease control OngoingThis study tests an experimental drug called LP352 to see if it can safely reduce seizures in children and adults with developmental and epileptic encephalopathies (DEE), a group of severe epilepsy syndromes. About 320 participants will receive either LP352 or a placebo, and rese…
Phase 3 • Sponsor: Longboard Pharmaceuticals • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New drug LP352 aims to control seizures in severe epilepsy over the long term
Disease control By invitation onlyThis phase 3 study is testing the long-term safety and effectiveness of LP352 (Bexicaserin) in 324 children and adults with developmental and epileptic encephalopathy (DEE), including Dravet and Lennox-Gastaut syndromes. Participants who completed earlier studies will receive LP3…
Phase 3 • Sponsor: Longboard Pharmaceuticals • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Gene therapy hope for toddlers with rett syndrome
Disease control OngoingThis study tests a one-time gene therapy called TSHA-102 in girls aged 2 to 4 with Rett syndrome, a severe genetic disorder. The therapy is given as a single injection into the spine. The main goal is to check if it is safe and tolerable, and to see early signs of whether it help…
Phase 3 • Sponsor: Taysha Gene Therapies, Inc. • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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Could probiotics soothe tummies in kids with autism?
Disease control OngoingThis study tests whether a daily probiotic supplement can improve the balance of gut bacteria in children aged 3 to 7 who have autism and digestive issues like constipation or stomach pain. Over 6 months, 60 children will receive either the probiotic or a placebo. The main goal i…
Sponsor: ProbiSearch SL • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Can a dopamine-blocking drug safely control tourette syndrome over years?
Disease control OngoingThis trial investigates the long-term safety of ecopipam, a drug that blocks dopamine D1 and D5 receptors, in children, adolescents, and adults with Tourette syndrome. Participants who completed a prior study may enroll and receive ecopipam for up to 24 weeks or longer. The main …
Phase 3 • Sponsor: Emalex Biosciences Inc. • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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New gene therapy hopes to restore milestones in rett syndrome
Disease control OngoingThis study tests a one-time gene therapy called TSHA-102 in females aged 6 to under 22 with classic Rett syndrome. The goal is to see if it is safe and can help them regain or gain new developmental skills like walking or talking. Participants receive the therapy through a spinal…
Phase 3 • Sponsor: Taysha Gene Therapies, Inc. • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Tailored milk boosts preemie brain growth?
Disease control OngoingThis study compares two ways of fortifying breast milk for preterm babies in the NICU. One group gets standard fortification, while the other gets a personalized mix based on real-time milk analysis. Researchers will track growth, brain scans, and development up to age 2 to see w…
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Gene therapy trial aims to help girls with rett syndrome gain new skills
Disease control OngoingThis study tests a gene therapy called NGN-401 in 33 girls with Rett syndrome, a rare genetic disorder that affects development and movement. The therapy delivers a working copy of the MECP2 gene to try to improve skills and daily function. Researchers will measure success by whe…
Phase 3 • Sponsor: Neurogene Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Nasal gene therapy offers new hope for brain injury patients
Disease control By invitation onlyThis study follows 25 people aged 2 to 65 with cerebral palsy or brain damage from lack of oxygen who have already received a new gene therapy given as a nose spray. The therapy delivers 15 genes meant to repair the brain, reduce inflammation, and improve movement and thinking. R…
Sponsor: Healing Hope International • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Diabetes drug could help Babies' brains heal after birth injury
Disease control By invitation onlyThis early-stage trial tests whether metformin, a common diabetes drug, is safe and feasible for infants who suffered brain injury from lack of oxygen at birth. Thirty infants under 6 months old will receive metformin for 6 weeks, with close monitoring of kidney and liver functio…
Phase 1 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Gene therapy hope for girls with rare brain disorder
Disease control OngoingThis study tests a new gene therapy called TSHA-102 for girls aged 5 to 8 with Rett syndrome, a severe genetic disorder that affects brain development. The therapy is given as a single injection into the spinal fluid. The main goal is to check safety and side effects, while also …
Phase 1/2 • Sponsor: Taysha Gene Therapies, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Virtual reality could calm anxious kids with autism at the dentist
Symptom relief By invitation onlyThis study tests whether wearing a virtual reality (VR) headset during dental treatment can reduce fear and stress in children with mild intellectual disabilities or autism spectrum disorder. Two hundred children aged 6 to 12 will either receive standard dental care or use a VR h…
Sponsor: Semmelweis University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Robotic exoskeleton training shows promise for kids with movement disorders
Symptom relief OngoingThis small study tests whether adding robot-assisted walking training to regular physiotherapy can improve body composition (like muscle and fat) and daily function in children with cerebral palsy or similar conditions. Nine children will each receive both standard physiotherapy …
Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Can a simple drug calm catatonia in autistic teens? new study hopes so
Symptom relief OngoingThis pilot study tests whether benzodiazepines (midazolam and clonazepam) and, if needed, electroconvulsive therapy (ECT) can safely reduce catatonic symptoms in 30 adolescents aged 10–19 with profound autism. Participants first receive a midazolam challenge; those who respond th…
Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Can a 6-Week zoom therapy help kids at risk for depression? st. louis schools test new approach
Symptom relief By invitation onlyThis study tests a 6-8 week caregiver-child therapy called THRIVE, delivered by school counselors via video or in school, to improve emotional and behavioral health in children aged 3-7 who are near the clinical threshold for mental health problems. THRIVE is compared to an onlin…
Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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School program aims to ease Kids' anxiety and depression
Symptom relief OngoingThis study tests a classroom program called the Kids' Empowerment Program (KEP) to help children ages 6 to 12 reduce symptoms of anxiety and depression. About 120 children will take part, with some starting the program right away and others later. The goal is to give kids practic…
Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Robot suit helps kids with movement disorders take steps at home
Symptom relief OngoingThis study tests a wearable robotic exoskeleton called EXPLORER in 15 children with movement problems from conditions like cerebral palsy. The goal is to see if it helps them walk better in their everyday environments, such as home and the community. The study focuses on safety, …
Sponsor: MarsiBionics • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Brain zaps may tame sensory overload in kids with autism
Symptom relief By invitation onlyThis study tests whether a non-invasive brain stimulation technique called cTBS can improve how children with autism (ages 6-12) combine what they see and hear. Forty children will receive either real or sham stimulation over 10 sessions. Researchers will use brain scans, genetic…
Sponsor: Neurolab Plus • Aim: Symptom relief
Last updated Jun 26, 2026 19:17 UTC
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Brain zaps for ADHD? new study tests iTBS in children
Symptom relief By invitation onlyThis study tests whether a non-invasive brain stimulation technique called iTBS can improve attention and self-control in children aged 6 to 12 with ADHD. Over two weeks, 40 children will receive either real or sham stimulation, and researchers will measure changes in attention u…
Sponsor: Neurolab Plus • Aim: Symptom relief
Last updated Jun 26, 2026 19:15 UTC
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Can Early-Life factors steer preterm and term infant health?
Knowledge-focused OngoingThis study follows mother-infant pairs from birth to 24 months to see how early nutrition, environmental exposures, and family factors relate to growth, development, and allergies in preterm and term infants. Researchers will use questionnaires and biological samples to examine h…
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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Could air pollution before birth raise ADHD risk? new brain scan study aims to find out
Knowledge-focused By invitation onlyThis study looks at whether air pollution exposure before birth is linked to ADHD risk in Puerto Rican children. Researchers will use brain scans (MRI) in 182 kids aged 6-11 to examine brain areas tied to attention. They also want to see if inflammation during pregnancy or sleep …
Sponsor: New York State Psychiatric Institute • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Can a nasal spray help autism symptoms? new study investigates
Knowledge-focused By invitation onlyThis study follows about 12 children and young adults (ages 4 to 21) with autism who are already using intranasal insulin as part of their regular care. Researchers want to see if this treatment is safe and if it helps with social skills, communication, and behavior over 6 months…
Sponsor: Healing Hope International • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Home visits for moms may boost child development and Well-Being
Knowledge-focused By invitation onlyThis study tests whether a home visiting program for mothers facing stress or past trauma can improve their mental health and their child's emotional and behavioral development. Researchers will follow 352 mother-child pairs from pregnancy until the child is 18 months old. They w…
Sponsor: IRCCS Eugenio Medea • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Smart sensors could spot motor delays in babies early
Knowledge-focused OngoingThis study tests whether wearable sensors and video recordings can help detect motor development problems in infants from birth to 24 months. Researchers will compare data from these devices with standard clinical tests. The goal is to create a more precise and automated way to i…
Sponsor: Shirley Ryan AbilityLab • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC