Brain zaps may tame sensory overload in kids with autism
NCT ID NCT07182331
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive brain stimulation technique called cTBS can improve how children with autism (ages 6-12) combine what they see and hear. Forty children will receive either real or sham stimulation over 10 sessions. Researchers will use brain scans, genetic tests, and sensory tasks to see if the treatment works and who benefits most.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- continuous theta-burst stimulation (cTBS) - a type of non-invasive brain stimulation
- What this could lead to
- If it works, this could point toward a non-drug treatment to help children with autism process sights and sounds more easily, potentially reducing sensory overload.
- What could go wrong
- This is a small, early-stage study with only 40 children. The treatment may not work better than sham stimulation, and results may not apply to all children with autism. Brain stimulation can sometimes cause discomfort or headache.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 6-12 years at the time of enrollment. * Clinical diagnosis of Autism Spectrum Disorder (ASD) confirmed using the Autism Diagnostic Interview-Revised (ADI-R). * Intelligence quotient (IQ) ≥ 70 as measured by the General Ability Index (GAI) from the Wechsler Intelligence Scale for Children - Fifth Edition (WISC-V). * Ability to understand and follow simple instructions for behavioral tasks and stimulation procedures. * Stable medication regimen (if any) for at least 4 weeks before the start of the study. * Written informed consent from a parent or legal guardian, and assent from the child when appropriate. Exclusion Criteria: * History of epilepsy, seizures, or abnormal EEG suggestive of seizure risk. * Presence of metal implants, devices, or foreign bodies in or near the head (except dental fillings) that are contraindicated for TMS or MRI. * Serious neurological disorders other than ASD (e.g., cerebral palsy, brain injury, neurodegenerative disease). * Severe psychiatric disorders requiring hospitalization or urgent intervention. * Current or past history of significant head trauma with loss of consciousness \> 5 minutes. * Uncorrected hearing or vision problems that could interfere with task performance. * Inability to tolerate sitting still for 15-20 minutes. * Participation in another interventional clinical trial within the past 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Neurolab Plus
Almaty, 050000, Kazakhstan
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Non-profit joint-stock company "Al-Farabi Kazakh National University"
Almaty, 050040, Kazakhstan
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Other studies related to the condition(s) this trial covers.
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- Can a stressful task reveal the Sleep-Learning link in neurodevelopmental disorders?