Nephrotic syndrome
MONDO:0005377A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction.
Also known as: nephrotic syndrome, nephrotic syndromes, syndrome, nephrotic, syndromes, nephrotic, nephrosis
71 clinical trials for this condition and its sub-types, 47 tagged with Nephrotic syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Nephrotic syndrome
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Idiopathic nephrotic syndrome 13 trials · 24 incl. sub-types
5 sub-types
- Idiopathic multidrug-resistant nephrotic syndrome 6 trials
- Idiopathic steroid-sensitive nephrotic syndrome 4 trials Sub-types →
- Sporadic idiopathic steroid-resistant nephrotic syndrome 0 trials · 2 incl. sub-types Sub-types →
- Familial idiopathic steroid-resistant nephrotic syndrome 0 trials Sub-types →
- Idiopathic steroid-resistant nephrotic syndrome with sensitivity to second-line immunosuppressive therapy 0 trials
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Familial nephrotic syndrome 0 trials · 22 incl. sub-types
18 sub-types
- Immunoglobulin-mediated membranoproliferative glomerulonephritis 12 trials
- Idiopathic multidrug-resistant nephrotic syndrome 6 trials
- Nephrotic syndrome 14 3 trials
- Nephrotic syndrome, type 4 1 trial
- LAMB2-related infantile-onset nephrotic syndrome 0 trials Sub-types →
- Congenital nephrotic syndrome, Finnish type 0 trials
- Familial idiopathic steroid-resistant nephrotic syndrome 0 trials Sub-types →
- Nephrotic syndrome 15 0 trials
- Nephrotic syndrome 16 0 trials
- Nephrotic syndrome, IIa 26 0 trials
- Nephrotic syndrome, type 17 0 trials
- Nephrotic syndrome, type 18 0 trials
- Nephrotic syndrome, type 19 0 trials
- Nephrotic syndrome, type 20 0 trials
- Nephrotic syndrome, type 21 0 trials
- Nephrotic syndrome, type 22 0 trials
- Nephrotic syndrome, type 23 0 trials
- Nephrotic syndrome, type 24 0 trials
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Steroid-resistant nephrotic syndrome 5 trials · 15 incl. sub-types
4 sub-types
- Nephrotic syndrome of childhood - steroid sensitive 5 trials
- Nephrotic syndrome 14 3 trials
- Sporadic idiopathic steroid-resistant nephrotic syndrome 0 trials · 2 incl. sub-types Sub-types →
- Familial idiopathic steroid-resistant nephrotic syndrome 0 trials Sub-types →
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Nephrotic syndrome ocular anomalies 0 trials
Most studied deeper sub-types
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Can a common statin help kids with kidney disease and high cholesterol?
Disease control CompletedThis completed Phase 4 trial tested the drug atorvastatin (Lipitor) in 100 children aged 8-18 with steroid-sensitive nephrotic syndrome and high cholesterol. The goal was to see if the drug safely lowers cholesterol to healthy levels within 3 to 6 months. The study compared atorv…
Phase 4 • Sponsor: National Institute of Kidney Disease and Urology (NIKDU) • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Common antibiotic may speed remission in kids with kidney disease
Disease control CompletedThis study tested whether adding the antibiotic azithromycin to standard steroid treatment helps children with steroid-sensitive nephrotic syndrome achieve remission faster. 160 children aged 2 to 14 were split into two groups: one received azithromycin plus steroids, the other o…
Phase 1 • Sponsor: University of Child Health Sciences and Children's Hospital, Lahore • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New hope for kids with kidney disease: rituximab cuts relapse risk
Disease control CompletedThis study tested whether rituximab, a medication that targets certain immune cells, could help children with a challenging form of nephrotic syndrome (a kidney disease) that keeps coming back. 91 children were split into two groups: one received rituximab plus special nursing ca…
Sponsor: Wuhan Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Vitamin d study aims to protect kidneys in children
Disease control CompletedThis study tested whether the usual vitamin D doses given to children with chronic kidney disease, kidney transplants, or nephrotic syndrome are enough to raise their vitamin D levels to a healthy range. Forty-three children received vitamin D vials based on their weight and star…
Phase 4 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 26, 2026 13:38 UTC
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Immune cells may hold key to predicting kidney disease relapse
Knowledge-focused CompletedThis study looks at immune cell patterns in people with three types of nephrotic syndrome—membranous nephropathy, minimal change disease, and focal segmental glomerulosclerosis. Researchers aim to see if certain immune cells can serve as biomarkers to track how well a patient res…
Sponsor: University Hospital, Ioannina • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC