Nephrotic syndrome, type 2
MONDO:0010974Any nephrotic syndrome in which the cause of the disease is a mutation in the NPHS2 gene.
Also known as: NPHS2 nephrotic syndrome, nephrotic syndrome caused by mutation in NPHS2, nephrotic syndrome, type 2, NPHS2, SRN1, nephrotic syndrome, idiopathic, steroid-resistant, nephrotic syndrome, steroid-resistant, autosomal recessive
4 clinical trials for this condition and its sub-types, 0 tagged with Nephrotic syndrome, type 2 itself.
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Could a diabetes drug protect kidneys in children with genetic disease?
Disease control Recruiting nowThis study tests whether adding dapagliflozin (a diabetes drug) to standard care reduces protein leakage in the urine of children with hereditary kidney diseases. About 44 children will receive either dapagliflozin plus standard care or standard care alone for 12 weeks, then swit…
Phase 3 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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China launches massive kidney registry to map nephrotic syndrome
Knowledge-focused Recruiting nowResearchers at Sun Yat-sen University are building a registry of people with nephrotic syndrome across hospitals in China. The study aims to enroll 5,000 patients regardless of the underlying cause. By recording baseline and follow-up information, the team will track kidney funct…
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC
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Personalized trial matching could revolutionize kidney disease treatment
Knowledge-focused Recruiting nowThis study helps people with certain kidney diseases (like nephrotic syndrome and FSGS) find clinical trials that match their specific disease profile. Researchers analyze participants' molecular data to recommend targeted therapies in ongoing trials. The goal is to improve treat…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Scientists hunt for hidden antibodies in Kids' kidney disease
Knowledge-focused Recruiting nowThis study is investigating whether certain autoantibodies, especially those targeting a protein called nephrin, play a role in nephrotic syndrome, a kidney condition that causes swelling and protein loss in urine. Researchers will analyze blood and kidney tissue from 50 children…
Sponsor: Meyer Children's Hospital IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC