Neonatal ichthyosis-sclerosing cholangitis syndrome
MONDO:0011874Neonatal ichthyosis-sclerosing cholangitis (NISCH syndrome) is a very rare complex ichthyosis syndrome characterized by scalp hypotrichosis, scarring alopecia, ichthyosis and sclerosing cholangitis.
Also known as: IHSC, NISCH syndrome, ichthyosis-hypotrichosis-sclerosing cholangitis syndrome, neonatal ichthyosis-sclerosing cholangitis syndrome, ILVASC, Ilvasc, Nisch syndrome, ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis
6 clinical trials for this condition and its sub-types, 0 tagged with Neonatal ichthyosis-sclerosing cholangitis syndrome itself.
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New ointment shows promise for rare skin condition
Disease control CompletedThis Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…
Phase 3 • Sponsor: LEO Pharma • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New imaging tool aims to sharpen bile duct diagnosis
Diagnosis CompletedThis completed study tested a device called NvisionVLE® that helps doctors see bile duct details during a procedure called ERCP. Only 3 adults who had the procedure between 2017 and 2019 took part. The goal was to check if the device is safe and can better find abnormalities to g…
Sponsor: Methodist Health System • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC