Nasal disorder

This study looked at whether treating the dental cause of chronic maxillary sinusitis with dental procedures and medication could resolve symptoms. Only 16 patients were enrolled before the study was terminated. The main goal was to see if symptoms disappeared and pus cleared fro…

This small, early-stage trial tested a combination of a steroid spray (triamcinolone) and a decongestant spray (oxymetazoline) to help people who were dependent on decongestants stop using them. The study planned to slowly reduce the decongestant dose while keeping the steroid st…

This phase 3 study tested the drug benralizumab in 295 adults with severe nasal polyps and eosinophilic chronic sinusitis. Participants received injections of benralizumab or a placebo every 4 to 8 weeks for about a year. The goal was to see if the drug could shrink polyps and im…

This study compared a newer, less invasive procedure called balloon sinuplasty to standard surgery for people with frontal sinusitis that did not improve with medication. The balloon procedure uses a small catheter to open blocked sinus passages, aiming to reduce pain, bleeding, …

This study tested whether teaching teens and young adults (ages 14-29) the correct way to use nasal sprays for hay fever would improve their symptoms compared to standard care. The trial was terminated early and enrolled only 18 participants. The goal was to see if repeat educati…

This study tested whether using the SinuSonic device—a handheld tool that uses sound and gentle pressure to relieve nasal congestion—could also improve anxiety, depression, and overall well-being in adults with chronic stuffy nose. Sixteen participants used the device for 5 weeks…

This study aimed to track lung function in children born prematurely (before 37 weeks) aged 3 to 5 years, comparing them to full-term children. Researchers used breathing tests and samples to look for early signs of asthma and allergies. The study was terminated early, so results…