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Multiple system atrophy, parkinsonian type
MONDO:0020352Multiple system atrophy, parkinsonian type (MSA-p) is a form of multiple system atrophy (MSA) with predominant parkinsonian features (bradykinesia, rigidity, irregular jerky postural tremor, and postural instability).
Also known as: MSA, parkinsonian type, MSA-p
36 clinical trials for this condition and its sub-types, 12 tagged with Multiple system atrophy, parkinsonian type itself.
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Spinal zap trial aims to steady blood pressure in Parkinson's patients
Disease control Recruiting nowThis early study tests a spinal cord stimulation therapy called ARC-IM in 5 people with Parkinson's disease or related conditions who experience severe drops in blood pressure when standing (orthostatic hypotension). The main goal is to check safety, and researchers will also mea…
Sponsor: Ecole Polytechnique Fédérale de Lausanne • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Brain cell transplant trial offers hope for rare Parkinson's-Like disease
Disease control Recruiting nowThis early-stage trial tests a single injection of dopamine-producing cells directly into the brain for people with multiple system atrophy (MSA), a rare and severe movement disorder. The main goal is to check safety and side effects in 9 participants aged 30 to 70. Researchers w…
Phase 1 • Sponsor: iRegene Therapeutics Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New protein therapy hopes to repair brain damage in rare disease
Disease control Recruiting nowThis early-phase trial tests a drug called Aleeto, a nerve repair protein made from stem cells, in 20 people with Multiple System Atrophy (MSA), a rare brain disease. The study checks if Aleeto is safe and might help with symptoms. Participants receive the drug via injection into…
Early phase 1 • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 26, 2026 12:56 UTC
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Could tweaking a common Parkinson's drug prevent fainting spells?
Symptom relief Recruiting nowThis study looks at whether changing the ratio of carbidopa to levodopa in standard Parkinson's medication can reduce orthostatic hypotension—a sudden drop in blood pressure when standing that causes dizziness and fainting. Researchers will give 36 patients with Parkinson's disea…
Phase 1/2 • Sponsor: Julien Bally • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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DNA hunt for rare brain disease genes begins
Knowledge-focused Recruiting nowThis study collects DNA from up to 1,000 adults with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), multiple system atrophy (MSA), or related conditions, plus their family members. Researchers will sequence participants' whole genomes to find genetic variants …
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC