Mucopolysaccharidosis type 1

MONDO:0001586

The most common type of mucopolysaccharidosis. It is inherited in an autosomal recessive pattern. It comprises a group of lysosomal storage diseases which includes the most severe form (Hurler syndrome) and the mildest form (Scheie syndrome).

Also known as: Alpha-L-iduronidase deficiency, MPS1, MPSI, Mucopolysaccharidosis Type I, lipochondrodystrophy, mucopolysaccharidosis type 1, mucopolysaccharidosis type I, Hurler syndrome

19 clinical trials for this condition and its sub-types, 11 tagged with Mucopolysaccharidosis type 1 itself.

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Where it sits in the disease tree

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Part of

↑ Bone disorder (6305) ↑ Eye disorder (3079) ↑ Mucopolysaccharidosis (62)

Sub-types of Mucopolysaccharidosis type 1

Including sub-types (19) Tagged with Mucopolysaccharidosis type 1 (11)

Trials to join now! 5 Not yet recruiting 1 Not yet finished but already full! 10 Completed 2 Terminated 1

New study aims to unmask hidden causes of childhood joint stiffness

Knowledge-focused Not yet recruiting

This study will look at 35 children with joint problems that are not caused by inflammation, such as stiffness or deformity. Researchers will use exams, lab tests, and imaging to find the true cause, which could be rare genetic conditions like mucopolysaccharidoses or osteogenesi…

Sponsor: Assiut University • Aim: Knowledge-focused

Last updated Jun 26, 2026 17:17 UTC

Mucopolysaccharidosis type 1

Where it sits in the disease tree

New study aims to unmask hidden causes of childhood joint stiffness