Mitral valve stenosis

This study is testing a new device called the Cephea Mitral Valve System for people with mitral valve disease (leaky or narrowed heart valves) who cannot have open-heart surgery. The goal is to see if the device is safe and works well. About 20 people will take part.

This study tests a new device called Tendyne, which is a replacement heart valve placed through a tube in the blood vessels, avoiding open-heart surgery. It is for people with a leaky mitral valve (mitral regurgitation) who are too high-risk for traditional surgery. The trial com…

This study tracks how well the MITRIS RESILIA mitral valve works in real-world patients who need a new mitral valve due to narrowing or leakage. About 504 adults having valve replacement surgery will be followed for safety and performance, including valve function and major heart…

This study compares dabigatran (Pradaxa) to warfarin for preventing strokes in 370 people with both atrial fibrillation and moderate-to-severe mitral stenosis. Participants are randomly assigned to one of the two blood thinners. The goal is to see if dabigatran is as good as or b…

This study looks at whether doing a heart valve repair procedure early, before symptoms appear, is better than waiting and using standard care for people with moderate mitral stenosis. The trial includes 167 participants who have no symptoms but are at risk for future heart probl…

This study looks at 3500 people who had their mitral valve replaced to see if the original problem (narrowing, leaking, or both) affects how long the new valve lasts. Researchers will check echocardiograms and health records over time. The goal is to better understand why some re…