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Heart valve study: does your original problem predict replacement wear?

NCT ID NCT07151989

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 38 times

Summary

This study looks at 3500 people who had their mitral valve replaced to see if the original valve problem (narrowing, leakage, or both) affects how long the new valve lasts. Researchers will check echocardiograms and health records over time. The goal is to better understand why some replacement valves wear out faster than others.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Maastricht UMC+

    Maastricht, Maastricht, Netherlands

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors predict which replacement valves might wear out faster based on the original valve problem, leading to better follow-up care.

What could go wrong

This is an observational study, not a treatment trial. It only looks back at past data, so it cannot prove cause and effect. Results may not apply to all patients.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.