Mitral valve prolapse
MONDO:0004910A fairly common and often benign valvular heart disorder characterized by redundancy or hooding of mitral valve leaflets so that they prolapse into the left atrium, often causing mitral regurgitation. It is often a symptomless condition but may be marked by varied symptoms (e.g. chest pain, fatigue, dizziness, dyspnea, or palpitations) leading in some cases to endocarditis or ventricular tachycardia.
Also known as: barlow's syndrome, floppy mitral valve, mitral valve prolapse, mitral valve prolapse (disease), mitral valve prolapse syndrome, prolapse, mitral valve, valve, prolapse Of mitral, mitral valve prolapse, myxomatous
55 clinical trials for this condition and its sub-types, 12 tagged with Mitral valve prolapse itself.
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Sub-types of Mitral valve prolapse
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Familial mitral valve prolapse 0 trials · 1 incl. sub-types
3 sub-types
- MVP1 1 trial
- Mitral valve prolapse, myxomatous 2 0 trials
- Mitral valve prolapse, myxomatous 3 0 trials
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New heart valve offers hope for High-Risk patients
Disease control Not yet recruitingThis study tests a new heart valve (SAPIEN X4) in 125 people with mitral valve disease who are too high-risk for open-heart surgery. The valve is placed using a thin tube through a blood vessel, avoiding major surgery. The goal is to see if the valve is safe and improves heart fu…
Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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AI ultrasound could unmask silent heart disease in seniors
Diagnosis Not yet recruitingThis trial tests whether an AI-guided handheld ultrasound, used during routine primary care or geriatrics visits, can detect serious heart valve disease and weak heart muscle in adults aged 65 to 85 who have no known heart problems. Half of the participants will receive this quic…
Sponsor: University of Texas Southwestern Medical Center • Aim: Diagnosis
Last updated Aug 19, 2026 00:00 UTC
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Simple foam dressings may shield heart surgery patients from painful bedsores
Prevention Not yet recruitingThis study tests whether placing soft foam dressings on the skin before heart surgery can prevent pressure injuries (bedsores). About 80 adults having long heart surgeries will be enrolled. Researchers will check for new skin injuries after surgery and track how severe they are. …
Sponsor: Shih,Wen-Chi • Aim: Prevention
Last updated Jun 27, 2026 12:33 UTC
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New sedative may cut delirium risk in elderly heart surgery patients
Symptom relief Not yet recruitingThis study compares two sedatives, remimazolam and midazolam, to see which one causes less confusion (delirium) after heart valve surgery in people aged 65 and older. Delirium affects up to 70% of older heart surgery patients and can lead to longer hospital stays and memory probl…
Phase 4 • Sponsor: Yonsei University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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China maps a decade of heart valve care for its elderly
Knowledge-focused Not yet recruitingResearchers are running a national registry of hospitalized patients aged 60 and older who have moderate or severe heart valve disease. The study records the type of valve problem, symptoms, other conditions, treatments received, and complications. By comparing this group with pa…
Sponsor: Yongjian Wu, MD, PhD • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Could a Pre-Surgery digital boost improve heart surgery recovery?
Knowledge-focused Not yet recruitingThis study tests a personalized, digitally supported prehabilitation program for adults waiting for elective cardiac surgery. Participants receive education, psychosocial support, nutritional advice, and home-based exercise guidance during the routine 6-10 week preoperative perio…
Sponsor: Ludwig Boltzmann Institute for Digital Health and Prevention • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Heart drug warfarin under scrutiny for male fertility risks
Knowledge-focused Not yet recruitingThis pilot study will follow 90 men aged 18-50 who need heart surgery, some of whom will take the blood thinner warfarin afterward. Researchers will track changes in sperm count, movement, shape, DNA health, and hormone levels over 12 months. The goal is to see if warfarin harms …
Sponsor: Città di Lecce Hospital, GVM Care & Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Heart surgery monitoring under the microscope: is the standard test accurate enough?
Knowledge-focused Not yet recruitingThis study will compare two ways of measuring pressure inside the heart during heart surgery: the gold standard (direct left atrial pressure) and a more common indirect method (pulmonary capillary wedge pressure). Researchers want to see if the indirect method is accurate enough …
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:15 UTC