Mitral valve disorder
MONDO:0003767A disease involving the mitral valve.
Also known as: disease of mitral valve, disease or disorder of mitral valve, disorder of mitral valve, mitral valve disease, mitral valve disease or disorder, mitral valve disorder, rheumatic disease of mitral valve, rheumatic mitral insufficiency
220 clinical trials for this condition and its sub-types, 48 tagged with Mitral valve disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Mitral valve disorder
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Mitral valve insufficiency 159 trials
1 sub-type
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Mitral valve stenosis 26 trials
1 sub-type
- Congenital mitral stenosis 0 trials
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Mitral valve prolapse 11 trials · 12 incl. sub-types
1 sub-type
- Familial mitral valve prolapse 0 trials · 1 incl. sub-types Sub-types →
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Inherited mitral valve disease 0 trials · 1 incl. sub-types
2 sub-types
- Familial mitral valve prolapse 0 trials · 1 incl. sub-types Sub-types →
- Congenital mitral stenosis 0 trials
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Mitral atresia disorder 0 trials
Most studied deeper sub-types
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Experimental heart valve device tested in just one patient — study halted
Disease control Stopped earlyThis early study tested a new device called the Cardiovalve Transfemoral Mitral Valve System in just one person with severe mitral regurgitation who was too high-risk for surgery. The device is inserted through a vein in the leg to replace the faulty mitral valve without open-hea…
Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Experimental heart slicing procedure tested on one patient
Disease control Stopped earlyThis early study tested a new procedure called SESAME that uses a wire threaded through blood vessels to slice away excess heart muscle in people with hypertrophic cardiomyopathy. Only one adult participated before the study was terminated. The goal was to see if the technique co…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Heart valve repair may unlock better drug dosing for heart failure
Knowledge-focused Stopped earlyThis registry tracks people with severe functional mitral regurgitation and heart failure who undergo a minimally invasive mitral valve repair called M-TEER. The goal is to see whether the repair allows patients to tolerate higher, guideline-recommended doses of heart failure med…
Sponsor: Institut für Pharmakologie und Präventive Medizin • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC