Metabolic bone disorder
MONDO:0800486A group of disorders that affect the bones secondary to increased levels of minerals or deficient levels of minerals such as calcium, magnesium, phosphorus, and vitamin D. Representative examples are osteomalacia, osteoporosis, and Paget disease.
317 clinical trials for this condition and its sub-types, 9 tagged with Metabolic bone disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Metabolic bone disorder
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Osteoporosis 278 trials · 296 incl. sub-types
7 sub-types
- Postmenopausal osteoporosis 53 trials
- Drug-induced osteoporosis 0 trials · 6 incl. sub-types Sub-types →
- Pregnancy associated osteoporosis 1 trial Sub-types →
- Premenopausal osteoporosis 1 trial
- X-linked osteoporosis with fractures 0 trials
- Idiopathic juvenile osteoporosis 0 trials
- Nephrolithiasis/osteoporosis, hypophosphatemic 0 trials Sub-types →
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Chondrocalcinosis 5 trials · 7 incl. sub-types
3 sub-types
- Chondrocalcinosis due to apatite crystal deposition 2 trials
- Chondrocalcinosis 1 0 trials
- Chondrocalcinosis 2 0 trials
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Osteomalacia 2 trials · 4 incl. sub-types
1 sub-type
- Oncogenic osteomalacia 3 trials
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Bone Paget disease 2 trials
5 sub-types
- Paget disease of bone 2, early-onset 0 trials
- Paget disease of bone 3 0 trials
- Paget disease of bone 6 0 trials
- Juvenile Paget disease 0 trials
- Paget disease of bone 4 0 trials
Most studied deeper sub-types
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A common supplement may shield bones in kidney disease — a trial puts it to the test
Disease control Stopped earlyThis pilot trial investigates whether potassium citrate can improve bone quality and strength in adults and children with chronic kidney disease. Participants take either potassium citrate or a placebo for six months, along with blood and urine tests and advanced bone scans. The …
Phase 2/3 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Could a common cholesterol drug protect bones and hearts after spinal injury?
Disease control Stopped earlyThis study tested whether the statin drug rosuvastatin, taken daily with supplements, could improve bone density and reduce heart disease risk in adults with long-term spinal cord injury. Only 8 people enrolled before the trial was stopped early. Participants received either rosu…
Phase 2 • Sponsor: Dr. B. Catharine. Craven • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Elderly arthritis study reveals hidden health risks
Knowledge-focused Stopped earlyThis study aimed to understand how age influences serious health issues like infections, cancer, heart disease, and bone fractures in people with rheumatoid arthritis. Researchers compared patients over 65 with younger adults (18-50) who had the same disease. The study was stoppe…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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HIV drugs may weaken bones: new study investigates
Knowledge-focused Stopped earlyThis study looked at bone density in HIV-positive men to see if antiretroviral drugs cause bone thinning. Researchers compared men starting HIV treatment with those not yet on therapy over two years. The goal was to understand why bone loss is more common in HIV patients.
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC