Macular holes
MONDO:0006843A hole in the macula of the retina.
Also known as: macular hole
31 clinical trials for this condition and its sub-types, 19 tagged with Macular holes itself.
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Could skipping Face-Down recovery be safe for macular hole surgery?
Disease control OngoingThis trial tests whether people with large macular holes (over 400 micrometres) can heal without the usual face-down positioning after surgery. All participants undergo a procedure called inverted flap vitrectomy with gas tamponade, and half are asked to avoid face-down posturing…
Sponsor: Lahore General Hospital • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Gas-Free eye surgery could revolutionize macular hole repair
Disease control OngoingThis study tests a new surgical technique to close macular holes in people with high myopia without using a gas bubble. The standard approach requires a gas bubble that blurs vision and forces patients to keep their head down for days. The new method uses a gel-like substance to …
Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Eye fluid analysis may unlock secrets of rare eye condition
Knowledge-focused OngoingThis pilot study examines proteins in the vitreous (the gel-like fluid inside the eye) of patients with pseudoexfoliation syndrome (PEX), a condition that can lead to glaucoma. Researchers will compare protein levels between eyes with and without PEX in 24 adults undergoing eye s…
Sponsor: Prim. Prof. Dr. Oliver Findl, MBA • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Eye surgery showdown: UNITY VCS vs CONSTELLATION trial pulled
Knowledge-focused CancelledThis study aimed to compare two surgical systems, UNITY VCS and CONSTELLATION, for treating various eye conditions like macular holes and retinal detachment. It was designed for adults needing vitreoretinal surgery. However, the trial was withdrawn before enrolling any participan…
Sponsor: Alcon Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC