Macular holes
MONDO:0006843A hole in the macula of the retina.
Also known as: macular hole
31 clinical trials for this condition and its sub-types, 19 tagged with Macular holes itself.
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Can a patch of the Eye's own tissue seal stubborn macular holes?
Disease control CompletedThis trial is testing whether a piece of the patient's own eye tissue, called Tenon's capsule, can help close large or recurrent macular holes—tears in the center of the retina that can blur or distort vision. During standard vitrectomy surgery, the tissue is harvested and placed…
Sponsor: Benha University • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could a tiny eye insert replace drops for kids after surgery?
Symptom relief CompletedThis early study tested a tiny dexamethasone insert placed in the tear duct of 15 children after retinal surgery or laser treatment. The goal was to see if it could safely reduce pain and eye inflammation. Researchers measured pain using a standard scale and tracked any side effe…
Early phase 1 • Sponsor: Lejla Vajzovic, MD, FASRS • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Built-In eye scanner could give surgeons a live 3D view during operations
Knowledge-focused CompletedThis study tests a microscope that has an OCT scanner built directly into it, allowing surgeons to take detailed cross-sectional images of the eye during surgery. The goal is to see if this setup is practical and whether the extra visual information helps guide surgical decisions…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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Blood thinners may be safe during retina surgery, study suggests
Knowledge-focused CompletedThis completed French study followed 748 adults undergoing retina/vitreous surgery to see if taking blood thinners (anticoagulants or antiplatelets) raises the risk of bleeding complications. Researchers compared patients who continued or stopped their medication with those not o…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scientists probe eye fluids to unlock secrets of retinal detachment
Knowledge-focused CompletedThis completed study looked at fluid samples from the eyes of 137 people undergoing surgery for retinal detachment or other eye conditions. Researchers measured fats and proteins in these fluids to understand inflammation and cell death that can harm vision after surgery. The goa…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC