Lung disorder
MONDO:0005275A disease involving the lung.
Also known as: disease of lung, disease or disorder of lung, disorder of lung, lung disease, lung disease or disorder, lung disorder, lung disorders, pulmonary disease
7078 clinical trials for this condition and its sub-types, 251 tagged with Lung disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lung disorder
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Lung neoplasm 1,367 trials · 4,039 incl. sub-types
10 sub-types
- Lung cancer 1,207 trials · 3,941 incl. sub-types Sub-types →
- Lung neuroendocrine neoplasm 21 trials · 540 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Lung PEComa 0 trials · 1 incl. sub-types Sub-types →
- Pulmonary sulcus neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
- Fibroma of lung 0 trials
- Hamartoma of lung 0 trials Sub-types →
- Lung germ cell tumor 0 trials
- Lung hilum neoplasm 0 trials Sub-types →
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Obstructive lung disease 36 trials · 1,071 incl. sub-types
1 sub-type
- Chronic obstructive pulmonary disease 935 trials · 1,051 incl. sub-types Sub-types →
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Respiratory failure 279 trials · 789 incl. sub-types
2 sub-types
- Acute respiratory failure 153 trials · 588 incl. sub-types Sub-types →
- Respiratory paralysis 20 trials
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Interstitial lung disease 256 trials · 728 incl. sub-types
14 sub-types
- Idiopathic pulmonary fibrosis 202 trials
- Interstitial lung disease specific to childhood 5 trials · 163 incl. sub-types Sub-types →
- Pulmonary fibrosis 140 trials · 143 incl. sub-types Sub-types →
- Bronchiolitis obliterans syndrome 42 trials · 44 incl. sub-types Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Secondary pulmonary hemosiderosis 0 trials · 30 incl. sub-types Sub-types →
- Interstitial lung disease specific to adulthood 0 trials · 20 incl. sub-types Sub-types →
- Radiation pneumonitis 20 trials
- Pneumoconiosis 5 trials · 13 incl. sub-types Sub-types →
- Inherited interstitial lung disease 5 trials · 11 incl. sub-types Sub-types →
- Drug or radiation exposure-related interstitial lung disease 2 trials
- Bronchiolocentric pattern of interstitial pneumonia 0 trials
- Isolated pulmonary capillaritis 0 trials
- Pulmonary fibrosis-hepatic hyperplasia-bone marrow hypoplasia syndrome 0 trials
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Pneumonitis 15 trials · 645 incl. sub-types
6 sub-types
- Pneumonia 326 trials · 610 incl. sub-types Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Radiation pneumonitis 20 trials
- Aspiration pneumonitis 2 trials Sub-types →
- Ichthyosis prematurity syndrome 1 trial
- Toxic pneumonitis 0 trials
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Bronchiolitis 51 trials · 104 incl. sub-types
6 sub-types
- Bronchiolitis obliterans syndrome 42 trials · 44 incl. sub-types Sub-types →
- Acute bronchiolitis 19 trials
- Respiratory syncytial virus bronchiolitis 6 trials
- Postinfectious bronchiolitis obliterans 2 trials
- Mac-Leod-Swyer-James-Syndrome 0 trials
- Toxic bronchiolitis 0 trials Sub-types →
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Acute lung injury 90 trials
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Fungal lung infectious disease 6 trials · 57 incl. sub-types
5 sub-types
- Pulmonary aspergilloma 11 trials · 38 incl. sub-types Sub-types →
- Pneumocystosis 19 trials
- Adiaspiromycosis 0 trials
- Cork-handlers' disease 0 trials
- Maple bark strippers' lung 0 trials
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Aspiration pneumonia 33 trials
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Acute chest syndrome 30 trials
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Middle lobe syndrome 29 trials
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Pulmonary systemic sclerosis 27 trials
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Pulmonary coin lesion 24 trials
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Pulmonary alveolar proteinosis 9 trials · 13 incl. sub-types
3 sub-types
- Autoimmune pulmonary alveolar proteinosis 6 trials
- Hereditary pulmonary alveolar proteinosis 3 trials · 6 incl. sub-types Sub-types →
- Secondary pulmonary alveolar proteinosis 0 trials
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Pulmonary artery disease 12 trials
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Restrictive pulmonary disease 8 trials
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Occupational lung disease 4 trials · 8 incl. sub-types
8 sub-types
- Occupational asthma 3 trials
- Bird fancier's lung 1 trial
- Bagassosis 0 trials
- Cork-handlers' disease 0 trials
- Farmer's lung disease 0 trials
- Malt worker's lung 0 trials
- Maple bark strippers' lung 0 trials
- Mushroom workers' lung 0 trials
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Neonatal aspiration syndrome 1 trial · 6 incl. sub-types
2 sub-types
- Meconium aspiration syndrome 5 trials
- Massive neonatal aspiration syndrome 0 trials
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Lung abscess 3 trials
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Pneumonic plague 3 trials
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Hantavirus pulmonary syndrome 2 trials
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Pulmonary immaturity 2 trials
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Wilson-Mikity syndrome 0 trials
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Dystrophic pulmonary ossification 0 trials
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Pulmonary alveolar microlithiasis 0 trials
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Pulmonary embolism and infarction 0 trials
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Pulmonary plasma cell granuloma 0 trials
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Pulmonary venoocclusive disease 0 trials
2 sub-types
- Pulmonary venoocclusive disease 1 0 trials
- Pulmonary venoocclusive disease 2 0 trials
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Shrinking lung syndrome 0 trials
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Silo filler disease 0 trials
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Vanishing lung syndrome 0 trials
Most studied deeper sub-types
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Can updated COVID-19 shots better protect High-Risk groups?
Vaccine Not yet recruitingThis Phase 3 trial tests updated versions of the BNT162b2 COVID-19 vaccine in adults and children aged 5 and older. Participants include those aged 5 to 64 with medical conditions that raise their risk of severe COVID-19, as well as everyone aged 65 and older. The study compares …
Phase 3 • Sponsor: BioNTech SE • Aim: Vaccine
Last updated Sep 03, 2026 00:00 UTC
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Experimental drug telaglenastat aims to lower lung blood pressure
Disease control Not yet recruitingThis study tests whether the drug telaglenastat, taken twice daily for 12 weeks, can safely lower blood pressure in the lungs and improve heart and lung function in adults with pulmonary hypertension. About 28 participants will receive the drug on top of their usual care. The mai…
Phase 1/2 • Sponsor: Chan, Stephen, MD, PhD • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Can a new injection ease COPD and cut Flare-Ups?
Disease control Not yet recruitingThis trial is testing an investigational drug called brenipatide in adults with moderate-to-severe COPD. Participants will receive either brenipatide or a placebo for about a year, alongside standard care. The goal is to see if brenipatide improves lung function and reduces the n…
Phase 2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Smart breathing machines at home could cut hospital visits for COPD patients
Disease control Not yet recruitingThis study looks at whether adding a home telemonitoring system to standard nighttime breathing support (non-invasive ventilation) can help people with severe COPD and high carbon dioxide levels. About 92 participants will be split into two groups: one using standard home ventila…
Sponsor: Air Liquide Healthcare Spain • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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New lung device aims to calm COPD symptoms
Disease control Not yet recruitingThis study tests a device that targets nerves in the lungs to help people with moderate to severe COPD breathe easier. About 300 participants will be randomly assigned to receive the real treatment or a sham procedure. Researchers will track symptoms, exercise ability, and flare-…
Sponsor: Ryme Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Desperate times: phage cocktail takes on Drug-Resistant lung bug
Disease control Not yet recruitingThis early study tests a special cocktail of viruses (phages) designed to attack a drug-resistant bacterium causing chronic lung infection. Only one person will receive the treatment alongside their usual antibiotics. The goal is to see if it's safe and can reduce the amount of b…
Phase 1 • Sponsor: Alberta Health services • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Cheaper keytruda copycat tested in lung cancer patients
Disease control Not yet recruitingThis phase 3 trial tests QL2107, a biosimilar (copy) of the cancer drug Keytruda, in 122 adults with non-small cell lung cancer that has been surgically removed. The goal is to see if the body processes QL2107 the same way as Keytruda when given as an extra treatment after surger…
Phase 3 • Sponsor: Qilu Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 14:56 UTC
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A breath sniff could one day screen for lung cancer and more
Diagnosis Not yet recruitingResearchers are testing whether an electronic nose that analyzes exhaled breath can serve as a noninvasive prescreening tool for several diseases at once. The study plans to enroll up to 20,000 adults and will first standardize the breath-sampling procedure, then evaluate how wel…
Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Diagnosis
Last updated Sep 06, 2026 00:00 UTC
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New blood test may spot silica lung damage before symptoms appear
Diagnosis Not yet recruitingThis study tests whether a specific antibody in the blood, called anti-CD146, can help doctors diagnose lung diseases caused by breathing in silica dust at work. Silica exposure can lead to serious lung problems like scarring, inflammation, and cancer, but there is currently no s…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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Caregiver burnout breakthrough? study tests Home-Based wellness program
Symptom relief Not yet recruitingThis study tests whether an 8-week virtual wellness program is practical and helpful for unpaid caregivers of people with advanced heart or lung disease. The program includes personalized exercise, nutrition advice, and stress management, all delivered at home with professional s…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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Can a scented massage boost brain function in ICU patients?
Symptom relief Not yet recruitingThis study will test whether a daily aromatherapy massage, combined with a sensory stimulation program, can improve cognitive function in intensive care patients with brain injuries. Sixty adults on ventilators or oxygen will be randomly assigned to receive the treatment from a f…
Sponsor: Nigde Omer Halisdemir University • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New nerve block technique aims to ease pain after lung surgery
Symptom relief Not yet recruitingThis study compares a new, simpler nerve block method to the traditional one for people having lung surgery with a camera (VATS). The goal is to see if the new method works just as well for pain control and helps patients recover faster. About 200 adults will be randomly assigned…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New oxygen device aims to ease breathing at home for chronically ill patients
Symptom relief Not yet recruitingThis study tests whether a new type of home oxygen therapy, called high-flow nasal cannula (HFNC), can improve breathing comfort and quality of life for people with long-term lung or heart conditions. Participants will try both HFNC and standard oxygen therapy for two weeks each …
Sponsor: Università degli Studi di Ferrara • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Smart sensors aim to predict dangerous COPD attacks before they happen
Knowledge-focused Not yet recruitingThis study follows 250 adults with severe COPD who use a breathing machine at home. Researchers collect data from sensors and regular check-ups to build a model that can warn of an upcoming flare-up. The goal is to catch problems early and reduce hospital visits.
Sponsor: Beijing Chao Yang Hospital • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Tight bands on legs may boost workout benefits for lung disease patients
Knowledge-focused Not yet recruitingThis study tests whether using a blood flow restriction (BFR) device during exercise can increase muscle fatigue in people with COPD, potentially making rehab more effective. Forty participants will do one session of resistance or cycling exercise with and without BFR. The goal i…
Sponsor: University Hospital, Grenoble • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Will a new electronic health record save lives? alberta launches massive study
Knowledge-focused Not yet recruitingThis study looks at whether a new province-wide electronic health record system (called Connect Care) improves outcomes for adults with chronic diseases like diabetes, heart failure, or kidney disease. Researchers will compare hospital readmission and death rates before and after…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Hormone-Brain link explored in new study
Knowledge-focused Not yet recruitingThis study looks at how the hormones estrogen and testosterone control blood flow to the brain. Researchers will temporarily block these hormones in 50 healthy young men and women, then measure brain blood flow and energy use. The goal is to understand sex differences in brain he…
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC