Li-fraumeni-like syndrome
MONDO:0800290Also known as: LFL
35 clinical trials for this condition and its sub-types, 3 tagged with Li-fraumeni-like syndrome itself.
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Scientists seek clues to rare cancer syndrome in 5,000-Person study
Knowledge-focused Recruiting nowThis study aims to learn more about Li-Fraumeni syndrome (LFS), a genetic condition that raises the risk of several cancers. Researchers will study up to 5,000 people with LFS or related cancer histories to find new genes, understand how the TP53 gene works, and identify factors …
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can a gene biobank unlock better cancer screening for Li-Fraumeni families?
Knowledge-focused Recruiting nowThis study creates a database and biobank for people with Li-Fraumeni syndrome or related TP53 gene changes, conditions that raise the lifetime risk of cancer to as high as 90%. Researchers will collect clinical data, blood samples, and tumor tissue from up to 300 participants to…
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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New registry aims to unlock secrets of rare cancer syndrome
Knowledge-focused Recruiting nowThis study is creating a registry for people with Li-Fraumeni syndrome, a rare genetic condition that raises the risk of several cancers. Researchers will collect medical, genetic, and quality-of-life data from 200 participants in Italy. The goal is to better understand the disea…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC