Lethal congenital contracture syndrome
MONDO:0017436A syndrome characterized by congenital nonprogressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth.
Also known as: LCCS
4 clinical trials for this condition and its sub-types, 0 tagged with Lethal congenital contracture syndrome itself.
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Browse by category →Sub-types of Lethal congenital contracture syndrome
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BioNTech launches trial of BNT326 for advanced cancers
Disease control Recruiting nowThis study tests a new drug called BNT326, given alone or with other cancer immunotherapies, in about 980 adults with advanced solid tumors that have spread or come back after prior treatment. The goal is to find the best dose and see if it is safe and effective. It is an early-s…
Phase 1/2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New combo therapy aims to tackle tough lung cancer
Disease control Recruiting nowThis study tests two experimental drugs, BNT326 and BNT327, in people with advanced non-small cell lung cancer that has spread or come back. The trial has three parts to find the best dose and check safety, and will compare the combination to standard treatments like pembrolizuma…
Phase 1/2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New lung cancer vaccine trial launches for advanced patients
Disease control Recruiting nowThis early-stage trial is testing a new cancer vaccine called BNT116, alone or with other drugs, in people with advanced non-small cell lung cancer. The main goal is to find a safe dose and check for side effects. About 320 participants will be enrolled across several groups, inc…
Phase 1 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC