Lethal congenital contracture syndrome

MONDO:0017436

A syndrome characterized by congenital nonprogressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth.

Also known as: LCCS

4 clinical trials for this condition and its sub-types, 0 tagged with Lethal congenital contracture syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disease (18235) ↑ Arthrogryposis syndrome (8)

Sub-types of Lethal congenital contracture syndrome

Lethal congenital contracture syndrome 2 3 trials
NEK9-related lethal skeletal dysplasia 0 trials
Fetal akinesia-cerebral and retinal hemorrhage syndrome 0 trials
Lethal congenital contracture syndrome 1 0 trials
Lethal congenital contracture syndrome 11 0 trials
Lethal congenital contracture syndrome 3 0 trials
Lethal congenital contracture syndrome 4 0 trials
Lethal congenital contracture syndrome 6 0 trials
Lethal congenital contracture syndrome 7 0 trials
Lethal congenital contracture syndrome 8 0 trials
Lethal congenital contracture syndrome 9 0 trials

Including sub-types (4) Tagged with Lethal congenital contracture syndrome (0)

Trials to join now! 3 Completed 1

Kids test new bionic foot design

Knowledge-focused Completed

This study tested a new prosthetic foot for children with leg amputations or birth defects. Thirteen kids walked with the device and gave feedback on stiffness and performance. The goal was to gather ideas to improve future foot designs.

Sponsor: Össur Iceland ehf • Aim: Knowledge-focused

Last updated Jun 27, 2026 14:00 UTC

Lethal congenital contracture syndrome

Where it sits in the disease tree

Kids test new bionic foot design