Leishmaniasis
MONDO:0011989Infectious disease that is transmitted through the bite of hematophagous female phlebotomine sand flies. The clinical spectrum ranges from asymptomatic to clinically overt disease which can remain localized to the skin or disseminate to the upper oral and respiratory mucous membranes or throughout the reticulo-endothelial system. Three main clinical syndromes have been described: visceral (or Kala-Azar; with fever, weight loss, hepatosplenomegaly), cutaneous, and mucocutaneous leishmaniasis (cutaneous or mucocutaneous ulceration).
Also known as: cutaneous leishmaniasis (subtype), visceral leishmaniasis (subtype)
28 clinical trials for this condition and its sub-types, 8 tagged with Leishmaniasis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Leishmaniasis
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Cutaneous leishmaniasis 14 trials
1 sub-type
- Leishmaniasis, diffuse cutaneous 0 trials
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Visceral leishmaniasis 14 trials
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Mucocutaneous leishmaniasis 3 trials
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New pill could cure parasitic skin disease in months
Cure Not yet recruitingThis study tests two doses of an experimental oral drug, LXE408, against a standard treatment (miltefosine) for localized cutaneous leishmaniasis, a parasitic skin disease. About 250 adults in the Americas will take the medicine for several weeks. The main goal is to see if the s…
Phase 2 • Sponsor: Drugs for Neglected Diseases • Aim: Cure
Last updated Jun 27, 2026 12:29 UTC
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Laser boost for leishmaniasis treatment?
Disease control Not yet recruitingThis study tests whether adding a fractional CO₂ laser to standard Glucantime injections helps heal skin sores from leishmaniasis faster and with less scarring. About 150 adults will be randomly assigned to get either the injection alone or the injection plus laser. Researchers w…
Phase 2 • Sponsor: Combined military hospital Peshawar • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Major trial launches to find better treatments for Flesh-Eating parasite
Disease control Not yet recruitingThis Phase 3 trial in Ethiopia will compare four different drug regimens against the standard treatment for cutaneous leishmaniasis, a parasitic skin disease. 900 patients aged 4 to 65 will be hospitalized and treated for up to 28 days, with follow-up for 6 months. The goal is to…
Phase 3 • Sponsor: Institute of Tropical Medicine, Belgium • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Could a gel heal parasite skin sores? new study begins
Disease control Not yet recruitingThis early study tests a gel made with the drug miltefosine for people with uncomplicated cutaneous leishmaniasis, a skin infection from a parasite. Fifteen adults will apply the gel to their sores daily for 28 days. The main goal is to see if the gel is safe and if it helps the …
Phase 1 • Sponsor: Universidad Industrial de Santander • Aim: Disease control
Last updated Jun 26, 2026 14:49 UTC
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AI app aims to help frontline workers diagnose neglected skin diseases
Diagnosis Not yet recruitingThis study tests whether a mobile app using artificial intelligence can help frontline health workers in sub-Saharan Africa better diagnose skin-related neglected tropical diseases, like leprosy and scabies. Researchers will collect images from dermatologists to train the AI, the…
Sponsor: Kenya Medical Research Institute • Aim: Diagnosis
Last updated Jun 27, 2026 12:04 UTC