Leiomyoma
MONDO:0001572A well-circumscribed benign smooth muscle neoplasm characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.
Also known as: fibroid, fibroid neoplasm, fibroid tumor, fibroid tumour, leiomyoma, benign, leiomyomatous neoplasm (morphologic abnormality), leiomyomatous tumour
1552 clinical trials for this condition and its sub-types, 74 tagged with Leiomyoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Leiomyoma
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Uterine corpus leiomyoma 104 trials · 109 incl. sub-types
11 sub-types
- Submucous uterine fibroid 3 trials
- Uterine corpus diffuse leiomyomatosis 2 trials
- Subserous uterine fibroid 0 trials
- Uterine corpus apoplectic leiomyoma 0 trials
- Uterine corpus bizarre leiomyoma 0 trials
- Uterine corpus cellular leiomyoma 0 trials
- Uterine corpus dissecting leiomyoma 0 trials
- Uterine corpus epithelioid leiomyoma 0 trials
- Uterine corpus lipoleiomyoma 0 trials
- Uterine corpus myxoid leiomyoma 0 trials
- Uterus interstitial leiomyoma 0 trials
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Myofibroma 17 trials
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Leiomyoma cutis 2 trials
1 sub-type
- Dartoic leiomyoma 0 trials
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Trachea leiomyoma 2 trials
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Leiomyomatosis 0 trials · 2 incl. sub-types
3 sub-types
- Uterine corpus diffuse leiomyomatosis 2 trials
- Disseminated peritoneal leiomyomatosis 0 trials
- Intravenous leiomyomatosis 0 trials Sub-types →
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Gastric leiomyoma 1 trial
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Benign metastasizing leiomyoma 0 trials
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Bizarre leiomyoma 0 trials
1 sub-type
- Uterine corpus bizarre leiomyoma 0 trials
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Bladder leiomyoma 0 trials
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Breast leiomyoma 0 trials
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Cellular leiomyoma 0 trials
1 sub-type
- Uterine corpus cellular leiomyoma 0 trials
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Central nervous system leiomyoma 0 trials
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Colorectal leiomyoma 0 trials
2 sub-types
- Colon leiomyoma 0 trials Sub-types →
- Rectum leiomyoma 0 trials Sub-types →
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Deep leiomyoma 0 trials
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Esophagus leiomyoma 0 trials
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Fallopian tube leiomyoma 0 trials
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Gallbladder leiomyoma 0 trials
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Laryngeal leiomyoma 0 trials
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Leiomyoma of ciliary body 0 trials
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Liver leiomyoma 0 trials
1 sub-type
- Extrahepatic bile duct leiomyoma 0 trials
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Lung leiomyoma 0 trials
1 sub-type
- Endobronchial leiomyoma 0 trials
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Mediastinum leiomyoma 0 trials
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Pericardium leiomyoma 0 trials
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Prostate leiomyoma 0 trials
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Renal leiomyoma 0 trials
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Small intestine leiomyoma 0 trials
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Ureter leiomyoma 0 trials
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Urethra leiomyoma 0 trials
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Vaginal leiomyoma 0 trials
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Vulvar leiomyoma 0 trials
Most studied deeper sub-types
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Can a Double-Wall bag stop leaks during keyhole fibroid surgery?
Disease control Not yet recruitingThis trial tests whether the LapBox Manual Containment System, a double-wall bag used during laparoscopic surgery, can prevent leaks when removing uterine fibroids. About 30 women having laparoscopic hysterectomy or myomectomy will use the device, and surgeons will check for any …
Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Can a One-Two punch shrink fibroids better?
Disease control Not yet recruitingThis trial tests whether adding a chemical injection to microwave ablation improves treatment for uterine fibroids, common non-cancerous tumors that can cause heavy bleeding and pain. Microwave ablation uses heat to destroy fibroid tissue, but blood flow can cool the area and red…
Sponsor: Peking University Aerospace Center Hospital • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Can a single injection curb blood loss in fibroid surgery?
Disease control Not yet recruitingThis trial tests whether injecting a diluted solution of terlipressin, a drug that narrows blood vessels, under the outer layer of a uterine fibroid before removal can reduce blood loss during myomectomy surgery. Women scheduled for myomectomy will be randomly assigned to receive…
Sponsor: Sevil Cankaya • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Fibroid removal before IVF: a Game-Changer for fertility?
Disease control Not yet recruitingThis study looks at whether surgically removing uterine fibroids (myomectomy) before in vitro fertilization (IVF) helps women with infertility have a baby. About 792 women aged 20-39 with fibroids 4-6 cm that do not distort the uterine cavity will be randomly assigned to either h…
Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New heat therapy could free women from fibroid surgery
Disease control Not yet recruitingThis study tests a minimally invasive treatment called microwave ablation for uterine fibroids. It uses heat to shrink fibroids and reduce symptoms like heavy bleeding and pelvic pressure, while preserving the uterus. The study will enroll 20 premenopausal women with fewer than f…
Sponsor: Jihad Hussien Mohamed Mahmoud • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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AI eye on the womb: new MRI model aims to spot hidden cancer
Diagnosis Not yet recruitingThis study will check if an artificial intelligence (AI) model can accurately tell the difference between common, non-cancerous uterine fibroids and a rare but serious cancer called uterine sarcoma using MRI scans. Researchers will enroll 500 women who are scheduled for surgery o…
Sponsor: Tongji Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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Could a common muscle relaxant cut narcotic use after hysterectomy?
Symptom relief Not yet recruitingThis study tests whether adding cyclobenzaprine, a muscle relaxant, to standard pain medicines (ibuprofen, acetaminophen, and short-term narcotics) improves pain control and reduces narcotic use after minimally invasive hysterectomy. About 36 women undergoing laparoscopic hystere…
Phase 4 • Sponsor: Christiana Care Health Services • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New surgical bag may speed up fibroid removal
Symptom relief Not yet recruitingThis trial tests a new single-channel bag used during keyhole surgery to remove uterine fibroids. The bag holds the fibroid while it is cut into smaller pieces, and the goal is to see if it makes the surgery faster and simpler than the current two-channel bag. About 78 women aged…
Sponsor: First People's Hospital of Hangzhou • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Could a tiny electrical zap ease pelvic pain after fibroid procedure?
Symptom relief Not yet recruitingThis study tests a device called TUNES, which delivers gentle electrical stimulation through a menstrual disc to nerves near the uterus. The goal is to see if it can reduce pain and the need for pain medication in 60 women after uterine fibroid embolization. Participants will be …
Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Battle of the scarless surgeries: which hysterectomy technique wins?
Symptom relief Not yet recruitingThis study compares two advanced, minimally invasive hysterectomy techniques—TU-LESS (through the belly button) and vNOTES (through the vagina)—in 210 women with an enlarged uterus. The goal is to see which method leads to faster recovery, less pain, and shorter hospital stays. P…
Sponsor: West China Second University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 17:42 UTC
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Which hysterectomy is better? new trial aims to find out
Symptom relief Not yet recruitingThis study compares total laparoscopic hysterectomy (removing the whole uterus including the cervix) with subtotal laparoscopic hysterectomy (keeping the cervix) in 500 women with benign conditions like fibroids or endometriosis. The main goal is to see which surgery leads to bet…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Jun 26, 2026 13:41 UTC
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Can big data improve safety in gynecologic surgery?
Knowledge-focused Not yet recruitingThis study is a large registry that will collect detailed information from thousands of women undergoing surgery for non-cancerous gynecologic conditions like fibroids, endometriosis, and ovarian cysts. The goal is to track surgical techniques, complications, and recovery in real…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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AI tool could make fibroid treatment more precise
Knowledge-focused Not yet recruitingThis study tests a new AI-powered software that helps doctors see, in real time, how well a minimally invasive fibroid treatment (uterine artery embolization) is working. The goal is to make the procedure more accurate and consistent. The study will involve 250 women with symptom…
Sponsor: Emanuele Barabino • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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AI model aims to predict Fibroid-Related infertility risk
Knowledge-focused Not yet recruitingThis study will test a computer model that predicts infertility risk in women with uterine fibroids. Researchers will follow over 7,000 women aged 20-50 who want to conceive and have fibroids. The goal is to see if the model can accurately identify who might struggle to get pregn…
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:28 UTC