Leber congenital amaurosis
MONDO:0018998Leber congenital amaurosis (LCA) is a retinal dystrophy defined by blindness and responses to electrophysiological stimulation (Ganzfeld electroretinogram (ERG)) below threshold, associated with severe visual impairment within the first year of life.
Also known as: Leber congenital amaurosis, amaurosis congenita of Leber, Leber's congenital tapetoretinal degeneration, Leber's congenital tapetoretinal dysplasia, congenital absence of the rods and cones, congenital retinal blindness
38 clinical trials for this condition and its sub-types, 11 tagged with Leber congenital amaurosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Leber congenital amaurosis
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Leber congenital amaurosis 2 3 trials
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Leber congenital amaurosis 10 2 trials
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Leber congenital amaurosis 5 2 trials
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Leber congenital amaurosis 1 1 trial
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Leber congenital amaurosis 11 0 trials
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Leber congenital amaurosis 12 0 trials
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Leber congenital amaurosis 13 0 trials
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Leber congenital amaurosis 14 0 trials
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Leber congenital amaurosis 15 0 trials
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Leber congenital amaurosis 16 0 trials
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Leber congenital amaurosis 17 0 trials
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Leber congenital amaurosis 18 0 trials
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Leber congenital amaurosis 19 0 trials
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Leber congenital amaurosis 3 0 trials
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Leber congenital amaurosis 4 0 trials
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Leber congenital amaurosis 6 0 trials
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Leber congenital amaurosis 7 0 trials
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Leber congenital amaurosis 8 0 trials
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Leber congenital amaurosis 9 0 trials
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Retinal aplasia 0 trials
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VR headsets tested as a possible treatment for blindness
Disease control Stopped earlyThis study tested whether using a virtual reality headset for one-hour sessions could help regenerate damaged optic nerves and improve vision in people with glaucoma or other retinal diseases. The idea came from promising results in rodents. However, the trial was terminated earl…
Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Scientists dig into DNA to unravel rare eye disorders
Knowledge-focused Stopped earlyThis study looked at over 100 people with inherited retinal dystrophies, a group of rare eye diseases that can cause vision loss. Researchers collected genetic and eye exam data to find links between specific gene mutations and symptoms. The goal was to better understand these di…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC