Language disorder

This study tests whether leucovorin calcium, a vitamin-like supplement, can improve language and other symptoms in young children with autism spectrum disorder. Researchers will enroll 80 children aged 2.5 to 5 years with language delays. The trial lasts about 26 weeks and compar…

This study tests a drug called neflamapimod in 20 people with a language disorder called nonfluent variant primary progressive aphasia (nfvPPA). The goal is to see if the drug is safe and if it can improve language symptoms. Participants will receive either the drug or a placebo …

This study explores whether joining a weekly reading group can improve reading comprehension and communication confidence in adults with aphasia, a language disorder often caused by stroke. Participants read a book at home and then discuss it in a 90-minute group session each wee…

This study tests whether folinic acid (leucovorin), a drug already used to reduce side effects from chemotherapy, can improve language skills in children with autism spectrum disorder. Researchers will give the drug or a placebo to 56 children aged 5 to 17 for 12 to 24 weeks and …

This study compares virtual reality-supported speech therapy to traditional speech therapy in 100 children aged 3 to 6 with developmental language disorder. Each child receives the same amount of therapy, but one group uses a VR system with touchscreen exercises while the other u…

This study tests a 22-week small-group program called Let's Know!2 for first graders with low language skills. The program uses fun lessons to build vocabulary and comprehension. Researchers will compare children who get the program to those who don't, tracking their progress thr…

This study follows children aged 6 to 21 who have a CNKSR2 gene mutation, which can cause epilepsy, language difficulties, and intellectual disability. Researchers will use brain scans, EEGs, and developmental tests to track how the condition changes over time. The goal is to cre…

This study compares 6 months of group music activities versus circus activities in 200 infants (8-12 months old) with or without a family history of dyslexia. Researchers will measure language skills, brain responses to sounds, and social-emotional factors. The goal is to see if …

This study looks at how the brain's temporal lobe helps process sound. Researchers will measure brain activity using EEG in 10 people who have had surgery to remove a lesion in a key hearing area. The goal is to better understand how the brain generates electrical responses to sp…