Juvenile dermatomyositis
MONDO:0008054Juvenile dermatomyositis (JDM) is the early-onset form of dermatomyositis (DM), a systemic, autoimmune inflammatory muscle disorder, characterized by proximal muscle weakness, evocative skin lesion, and systemic manifestations.
Also known as: childhood dermatomyositis, inflammation of myoseptum, juvenile DM, juvenile dermatomyositis, myoseptum inflammation, myoseptumitis, JDM, JPM
50 clinical trials for this condition and its sub-types, 41 tagged with Juvenile dermatomyositis itself.
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Can a One-Time cell therapy reset the immune system in autoimmune disease?
Cure Not yet recruitingThis trial is testing an experimental treatment called CRT-402 for people with severe autoimmune diseases like lupus, scleroderma, and myositis that haven't improved with standard therapies. CRT-402 is a type of CAR-T cell therapy given by infusion that aims to deplete certain im…
Phase 1/2 • Sponsor: Myeloid Therapeutics • Aim: Cure
Last updated Aug 23, 2026 00:00 UTC
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HIV drug repurposed to fight muscle inflammation
Disease control Not yet recruitingThis study tests whether Maraviroc, a drug currently used for HIV, can reduce muscle inflammation and improve function in adults with myositis that hasn't responded to standard treatments. Ten participants will take a daily 300mg tablet for 12 weeks and undergo muscle biopsies an…
Phase 4 • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Can an online program help young people with lupus and dermatomyositis feel less stressed?
Symptom relief Not yet recruitingThis study tests a new online program called TEAM-LEADS designed to help teens and young adults (ages 13-22) with lupus or dermatomyositis reduce stress and improve heart-healthy behaviors like diet, exercise, and sleep. The program is self-guided and completed online. The study …
Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Hypnosis may replace pills for Needle-Phobic kids
Symptom relief Not yet recruitingThis study tests whether hypnotherapy can reduce pain and anxiety in children aged 6 to 18 during needle procedures like injections or blood draws. About 70 kids with conditions like juvenile arthritis or lupus will be randomly assigned to receive either hypnotherapy or standard …
Sponsor: Aarhus University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Blood markers may spot Kids' lung disease earlier
Knowledge-focused Not yet recruitingThis study looks at whether two substances in the blood, IL-6 and MMP-7, can help doctors diagnose and predict the course of a rare lung disease in children. Researchers will measure these markers in 60 children with immune-mediated interstitial lung disease and compare them to h…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New eye on muscle disease: could a quick scan replace weeks of waiting?
Knowledge-focused Not yet recruitingThis study tests a new imaging technique called full-field OCT to see if it can spot muscle inflammation faster than the usual method, which takes weeks. Researchers will compare both methods on muscle samples from 20 healthy adults and people with suspected myositis. The goal is…
Sponsor: Centre Hospitalier de Mâcon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC