Intracranial embolism
MONDO:0006809Blocking of a blood vessel in the skull by an embolus which can be a blood clot (thrombus) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with heart diseases. Other non-cardiac sources of emboli are usually associated with vascular diseases.
62 clinical trials for this condition and its sub-types, 22 tagged with Intracranial embolism itself.
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New device closes heart pouch to stop strokes without blood thinners
Disease control CompletedThis study tested a device called the Lariat to close off a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who cannot take blood thinners. The goal was to reduce the risk of stroke. Nine participants were enrolled, and the study measured h…
Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New stroke drug shows promise in recovery trial
Disease control CompletedThis study tested a new medicine called MLC1501 to help people recover after a stroke. 303 adults who had a stroke within the past 2 to 10 days took either a high dose, low dose, or a placebo pill twice a day for 24 weeks. The main goal was to see if MLC1501 improves motor functi…
Phase 2 • Sponsor: Moleac Pte Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Heart CT scans may spot clots missed by standard tests
Diagnosis CompletedThis study combined data from nearly 4,000 stroke patients to see how often a heart CT scan finds blood clots that standard ultrasound might miss. Researchers looked at how well this quick scan, done during the initial stroke workup, detects clot sources in the heart. The goal is…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Diagnosis
Last updated Jun 27, 2026 08:13 UTC
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New wearable device could uncover hidden stroke cause
Diagnosis CompletedThis study tested a wearable heart monitor called Cardea SOLO against a standard 12-lead EKG to see if it could better detect paroxysmal atrial fibrillation (a temporary irregular heartbeat) in people who had a stroke of unknown cause and have an enlarged heart. 257 participants …
Sponsor: Asan Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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Heart valve study: which blood thinner best protects the brain?
Knowledge-focused CompletedThis study looked at 70 people who had a tissue heart valve replacement. It compared two common blood-thinning treatments (high-dose aspirin alone vs warfarin plus low-dose aspirin) to see which one better prevented tiny blood clots from traveling to the brain. Researchers used u…
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Heart scans may reveal hidden stroke risk in unexpected patients
Knowledge-focused CompletedThis small pilot study explored whether advanced heart imaging can detect hidden strokes in people who have never had atrial fibrillation but are at high risk due to conditions like diabetes or heart failure. Researchers used brain MRIs to find silent, symptom-free strokes and li…
Sponsor: Tulane University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Rare stroke cause gets closer look in new study
Knowledge-focused CompletedThis study looked at 79 people with a rare type of stroke caused by calcified particles traveling to the brain. Researchers used CT scans to describe the size, location, and density of these particles, and compared patients' medical histories and risk factors. The goal was to bet…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Heart clots leave unique brain marks after stroke
Knowledge-focused CompletedThis study looked at brain MRI scans of 122 stroke patients to see if those with a blood clot in the heart (intracardiac thrombus) had different patterns of brain damage compared to those with atrial fibrillation. Researchers analyzed the location, size, and number of stroke lesi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC