Intestinal disorder
MONDO:0005020A non-neoplastic or neoplastic disorder that affects the small or large intestine.
Also known as: disease of intestine, disease or disorder of intestine, disorder of intestine, intestinal disease, intestinal disorder, intestine disease, intestine disease or disorder, disease, intestinal
5443 clinical trials for this condition and its sub-types, 70 tagged with Intestinal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Intestinal disorder
-
Large intestine disorder 2 trials · 3,821 incl. sub-types
11 sub-types
- Colorectal neoplasm 1,495 trials · 2,900 incl. sub-types Sub-types →
- Colonic disorder 18 trials · 1,470 incl. sub-types Sub-types →
- Rectal disorder 22 trials · 793 incl. sub-types Sub-types →
- Disorder of appendix 1 trial · 132 incl. sub-types Sub-types →
- Polyp of large intestine 60 trials · 114 incl. sub-types Sub-types →
- Anal canal cancer 22 trials · 44 incl. sub-types Sub-types →
- Epithelial tumor of anal canal 0 trials · 34 incl. sub-types Sub-types →
- Shigellosis 14 trials
- Crohn's colitis 7 trials
- Benign neoplasm of large intestine 4 trials · 6 incl. sub-types Sub-types →
- Colorectal Kaposi sarcoma 0 trials Sub-types →
-
Intestinal neoplasm 4 trials · 3,080 incl. sub-types
6 sub-types
- Colorectal neoplasm 1,495 trials · 2,900 incl. sub-types Sub-types →
- Intestinal cancer 25 trials · 2,791 incl. sub-types Sub-types →
- Small intestine neoplasm 1 trial · 223 incl. sub-types Sub-types →
- Epithelial tumor of anal canal 0 trials · 34 incl. sub-types Sub-types →
- Intestinal neuroendocrine neoplasm 7 trials · 21 incl. sub-types Sub-types →
- Intestinal benign neoplasm 1 trial · 7 incl. sub-types Sub-types →
-
Inflammatory bowel disease 430 trials · 1,081 incl. sub-types
40 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Crohn disease 563 trials · 569 incl. sub-types Sub-types →
- Proctitis 2 trials · 21 incl. sub-types Sub-types →
- Inflammatory bowel disease 1 3 trials
- Undetermined colitis 3 trials
- Ulcerative proctosigmoiditis 2 trials
- ALPI-related inflammatory bowel disease 0 trials
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- TRIM22-related inflammatory bowel disease 0 trials
- Cap polyposis 0 trials
- Cutaneous photosensitivity-lethal colitis syndrome 0 trials
- Inflammatory bowel disease (infantile ulcerative colitis) 31, autosomal recessive 0 trials
- Inflammatory bowel disease 10 0 trials
- Inflammatory bowel disease 11 0 trials
- Inflammatory bowel disease 12 0 trials
- Inflammatory bowel disease 13 0 trials
- Inflammatory bowel disease 14 0 trials
- Inflammatory bowel disease 15 0 trials
- Inflammatory bowel disease 16 0 trials
- Inflammatory bowel disease 17 0 trials
- Inflammatory bowel disease 18 0 trials
- Inflammatory bowel disease 19 0 trials
- Inflammatory bowel disease 2 0 trials
- Inflammatory bowel disease 20 0 trials
- Inflammatory bowel disease 21 0 trials
- Inflammatory bowel disease 22 0 trials
- Inflammatory bowel disease 23 0 trials
- Inflammatory bowel disease 24 0 trials
- Inflammatory bowel disease 26 0 trials
- Inflammatory bowel disease 27 0 trials
- Inflammatory bowel disease 29 0 trials
- Inflammatory bowel disease 3 0 trials
- Inflammatory bowel disease 30 0 trials
- Inflammatory bowel disease 4 0 trials
- Inflammatory bowel disease 5 0 trials
- Inflammatory bowel disease 6 0 trials
- Inflammatory bowel disease 7 0 trials
- Inflammatory bowel disease 8 0 trials
- Inflammatory bowel disease 9 0 trials
- Neonatal inflammatory skin and bowel disease 0 trials Sub-types →
-
Gastroenteritis 20 trials · 839 incl. sub-types
9 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Appendicitis 76 trials
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Inflammatory diarrhea 0 trials · 33 incl. sub-types Sub-types →
- Enteritis 5 trials · 23 incl. sub-types Sub-types →
- Eosinophilic gastroenteritis 6 trials · 7 incl. sub-types Sub-types →
- Campylobacteriosis 3 trials Sub-types →
- Intestinal tuberculosis 2 trials
- Salmonella gastroenteritis 0 trials
-
Small intestine disorder 7 trials · 387 incl. sub-types
10 sub-types
- Small intestine neoplasm 1 trial · 223 incl. sub-types Sub-types →
- Duodenal disorder 1 trial · 109 incl. sub-types Sub-types →
- Celiac disease 81 trials Sub-types →
- Enteritis 5 trials · 23 incl. sub-types Sub-types →
- Pouchitis 18 trials
- Small intestinal bacterial overgrowth 18 trials
- Atresia of small intestine 0 trials
- Congenital short bowel syndrome 0 trials Sub-types →
- Small intestine diverticulitis 0 trials Sub-types →
- Small intestine duplication 0 trials Sub-types →
-
Irritable bowel syndrome 223 trials
-
Bowel dysfunction 11 trials · 211 incl. sub-types
1 sub-type
- Constipation disorder 189 trials · 202 incl. sub-types Sub-types →
-
Glucose-galactose malabsorption 2 trials · 151 incl. sub-types
1 sub-type
- Glucose intolerance 149 trials
-
Malabsorption syndrome 13 trials · 120 incl. sub-types
9 sub-types
- Celiac disease 81 trials Sub-types →
- Autoimmune enteropathy 2 trials · 11 incl. sub-types Sub-types →
- Lactose intolerance 9 trials · 10 incl. sub-types Sub-types →
- Idiopathic malabsorption due to bile acid synthesis defects 4 trials
- Intestinal disaccharidase deficiency 0 trials · 2 incl. sub-types Sub-types →
- Blind loop syndrome 1 trial
- Tropical sprue 1 trial
- Hereditary folate malabsorption 0 trials
- Lysine malabsorption syndrome 0 trials
-
Intestinal obstruction 44 trials · 91 incl. sub-types
6 sub-types
- Ileus 10 trials · 42 incl. sub-types Sub-types →
- Intestinal volvulus 4 trials
- Duodenal obstruction 2 trials · 3 incl. sub-types Sub-types →
- Encapsulating peritoneal sclerosis 2 trials
- Intussusception 2 trials
- Intestinal impaction 0 trials
-
Eosinophilic gastrointestinal disease 9 trials · 73 incl. sub-types
3 sub-types
- Eosinophilic esophagitis 67 trials Sub-types →
- Eosinophilic gastroenteritis 6 trials · 7 incl. sub-types Sub-types →
- Proton-pump inhibitor-responsive esophageal eosinophilia 0 trials
-
Intestinal fistula 6 trials · 63 incl. sub-types
1 sub-type
- Anal fistula 57 trials
-
Necrotizing enterocolitis 51 trials
1 sub-type
- Perinatal necrotizing enterocolitis 9 trials
-
Short bowel syndrome 39 trials
1 sub-type
- Secondary short bowel syndrome 0 trials
-
Intestinal motility disease 10 trials · 39 incl. sub-types
15 sub-types
- Hirschsprung disease 29 trials
- Multisystemic smooth muscle dysfunction syndrome 2 trials Sub-types →
- Goldberg-Shprintzen syndrome 0 trials
- Haddad syndrome 0 trials
- Hirschsprung disease-ganglioneuroblastoma syndrome 0 trials
- Hirschsprung disease-hearing loss-polydactyly syndrome 0 trials
- Hirschsprung disease-nail hypoplasia-dysmorphism syndrome 0 trials
- Hirschsprung disease-type D brachydactyly syndrome 0 trials
- Waardenburg-Shah syndrome 0 trials Sub-types →
- Chronic intestinal pseudoobstruction 0 trials Sub-types →
- Congenital diarrhea 6 0 trials
- Familial visceral myopathy 0 trials Sub-types →
- Intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency 0 trials
- Megacystis-microcolon-intestinal hypoperistalsis syndrome 0 trials Sub-types →
- Oculogastrointestinal muscular dystrophy 0 trials
-
Diverticulitis 28 trials · 34 incl. sub-types
2 sub-types
- Diverticulitis of colon 19 trials
- Small intestine diverticulitis 0 trials Sub-types →
-
Chronic intestinal failure 24 trials
-
Neurogenic bowel 22 trials
-
Postgastrectomy syndrome 2 trials · 20 incl. sub-types
2 sub-types
- Dumping syndrome 19 trials
- Afferent loop syndrome 0 trials
-
Hypertrophic pyloric stenosis 16 trials
2 sub-types
-
Parasitic intestinal disorder 0 trials · 16 incl. sub-types
7 sub-types
- Intestinal helminthiasis 3 trials · 9 incl. sub-types Sub-types →
- Cryptosporidiosis 5 trials
- Giardiasis 2 trials
- Protozoal dysentery 0 trials · 1 incl. sub-types Sub-types →
- Blastocystis infectious disease 0 trials
- Balantidiasis 0 trials
- Dientamoebiasis 0 trials
-
Ischemic bowel disorder 8 trials · 15 incl. sub-types
1 sub-type
- Acute intestinal ischemia 12 trials
-
Endometriosis of intestine 9 trials
-
Intestinal perforation 9 trials
2 sub-types
- Perinatal intestinal perforation 0 trials
- Spontaneous intestinal perforation 0 trials
-
Intestinal polyp 8 trials
-
Protein-losing enteropathy 7 trials
-
Intestinal atresia 3 trials · 6 incl. sub-types
2 sub-types
- Duodenal atresia 2 trials
- Multiple intestinal atresia 0 trials · 1 incl. sub-types Sub-types →
-
Refractory celiac disease 4 trials
-
Volvulus of midgut 4 trials
1 sub-type
-
Abetalipoproteinemia 2 trials
-
Pneumatosis cystoides intestinalis 2 trials
-
Angiodysplasia of intestine 1 trial
-
Steatorrhea 1 trial
1 sub-type
- Pancreatic steatorrhea 0 trials
-
4-hydroxyphenylacetic aciduria 0 trials
-
NK-cell enteropathy 0 trials
-
Satoyoshi syndrome 0 trials
-
Whipple disease 0 trials
-
Collagenous sprue 0 trials
-
Intestinal dysmotility syndrome 0 trials
-
Intestinal lymphangiectasia 0 trials
2 sub-types
- Primary intestinal lymphangiectasia 0 trials
- Secondary intestinal lymphangiectasia 0 trials
-
Isolated mesenteric vein thrombosis 0 trials
-
Malakoplakia 0 trials
-
Mucocele of appendix 0 trials
-
Primary desmosis coli 0 trials
-
Solitary rectal ulcer syndrome 0 trials
-
Trichohepatoenteric syndrome 0 trials
2 sub-types
- Trichohepatoenteric syndrome 1 0 trials
- Trichohepatoenteric syndrome 2 0 trials
Most studied deeper sub-types
-
New drug shows promise for managing short bowel syndrome Long-Term
Disease control OngoingThis study looks at the long-term safety and effectiveness of a drug called glepaglutide in adults with short bowel syndrome (SBS), a condition where the body can't absorb enough nutrients from food. Participants who were already in earlier trials can continue treatment for up to…
Phase 3 • Sponsor: Zealand Pharma • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
-
Could a single injection fix bowel leakage after childbirth? new trial aims to find out
Disease control OngoingThis Phase 3 trial tests a single injection of muscle cells (iltamiocel) into the anal sphincter to reduce accidental bowel leakage in women who have had a childbirth injury. About 200 women will receive either the cell injection or a placebo. The study measures how often leakage…
Phase 3 • Sponsor: Cook MyoSite • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
-
New drug cocktail shows promise for Hard-to-Treat colorectal cancer
Disease control OngoingThis study tests whether a combination of two targeted drugs (encorafenib and cetuximab), given alone or with chemotherapy, works better than standard chemotherapy for people with a specific genetic form of advanced colorectal cancer (BRAF V600E mutation) that has spread and hasn…
Phase 3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
-
Could stem cells and a special diet ease autism symptoms? new trial aims to find out.
Disease control By invitation onlyThis study tests whether a mix of treatments—including the patient's own stem cells, a strict keto diet, and a fecal transplant—can improve social skills, communication, and gut health in 50 teens and adults with autism. Participants must be stable on their current medications. T…
Phase 1/2 • Sponsor: Black Tie Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
-
Could ditching gluten ease two tough gut diseases?
Disease control OngoingThis study looks at whether a gluten-free diet can help people with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD). Researchers will track changes in symptoms, gut bacteria, and lab results in 60 adults over time. The goal is to see if avoiding gluten c…
Sponsor: Institute for Clinical and Experimental Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
-
Could a belly zapper cut bathroom time for spinal injury patients?
Symptom relief By invitation onlyMany people with spinal cord injury struggle with slow bowel emptying and constipation. This study tests whether a small device that delivers gentle electrical pulses to the belly can speed up bowel movements and improve stool consistency. Twelve participants will use the stimula…
Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
-
One-Time biofeedback may ease bowel troubles after rectal cancer surgery
Symptom relief By invitation onlyThis study tests whether adding a single, non-invasive biofeedback session to home Kegel exercises can improve bowel control, reduce emotional distress, and enhance quality of life in people who have had rectal cancer surgery. About 66 participants will be randomly assigned to ei…
Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
-
Peppermint oil: a natural fix for Kids' bathroom troubles?
Symptom relief By invitation onlyThis study is testing whether peppermint oil capsules can improve symptoms of bladder and bowel dysfunction in children aged 8 to 17 who haven't gotten better with standard behavioral therapy. Thirty participants will take peppermint oil three times daily for 8 weeks, and researc…
Sponsor: Children's Hospital of Orange County • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
-
One bite of gluten: scientists track the immune alarm in celiac disease
Knowledge-focused By invitation onlyResearchers at Boston Children's Hospital are studying how the immune system reacts after a single oral dose of gluten powder. The study includes people with celiac disease and healthy controls, all of whom follow a gluten-free diet before the test. By measuring blood levels of i…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
-
Blood test could spot returning colon cancer months before scans
Knowledge-focused OngoingThis study tests whether a simple blood test that looks for tumor DNA can detect colorectal cancer coming back earlier than standard CT scans. About 359 people who had surgery for stage II or III colorectal cancer will be randomly assigned to either the blood test plus frequent P…
Sponsor: Claus Lindbjerg Andersen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
-
Pill-Sized camera could unlock secrets of childhood malnutrition
Knowledge-focused By invitation onlyThis study tests whether a special camera capsule, swallowed like a pill, can safely take pictures of the small intestine in children with environmental enteric dysfunction (EED), a gut condition linked to malnutrition. Researchers will also use a thin tube camera through the nos…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
-
500 obese adults donate samples to unlock secrets of weight loss
Knowledge-focused OngoingThis study collects blood, urine, and tissue samples from 500 obese adults to help researchers understand why people gain weight, lose weight, or regain weight after treatment. Participants must be over 18 with a BMI of 30 or higher. The samples will be stored for up to 10 years …
Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC