Shigellosis
MONDO:0019345Shigellosis is a bacterial infection leading to dysentery and is caused by Shigella, which are small, ubiquitous Gram-negative bacteria belonging to the enterobacteria family. There are four species: S. dysenteriae, S. flexneri, S. boydii and S. sonnei, all of which cause bacillary dysentery and are strictly limited to human hosts.
Also known as: shigellosis, Shigella boydii infectious disease, Shigella flexneri infectious disease, Shigella sonnei infectious disease, Shigella dysentery, flexner's dysentery, japanese dysentery
18 clinical trials for this condition and its sub-types, 14 tagged with Shigellosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
New vaccine trial targets deadly diarrhea bug
Vaccine Recruiting nowThis early-stage study tests a new vaccine called IVT Shigella-04 to see if it is safe and helps the immune system fight Shigella bacteria, a major cause of severe diarrhea. About 60 healthy adults aged 18 to 49 will receive two shots of either the vaccine or a placebo. Researche…
Phase 1 • Sponsor: Inventprise Inc. • Aim: Vaccine
Last updated Jun 27, 2026 07:58 UTC
-
Could a simple antibiotic stop shigella from stunting Kids' growth?
Disease control Recruiting nowThis study looks at whether giving antibiotics to children with a certain type of Shigella infection (non-dysentery watery diarrhea) helps them recover faster and grow better. About 700 children in Bangladesh and Zambia will receive either azithromycin or a placebo. Researchers w…
Phase 2 • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
-
AI stethoscope aims to spot hidden heart and lung problems in children
Diagnosis Recruiting nowThis trial is developing an AI-powered device that listens to children's heart, breath, and bowel sounds to identify signs of common diseases like congenital heart disease, bronchopneumonia, and abdominal issues. It will involve 30,000 children aged 0-18, some with these conditio…
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Diagnosis
Last updated Aug 14, 2026 00:00 UTC
-
Simple handwashing program could curb cholera outbreaks
Prevention Recruiting nowThis study tests a program called CHoBI7, which teaches handwashing, water treatment, and safe water storage to diarrhea patients and their families in Bangladesh hospitals. Researchers want to see if this program reduces diarrhea and improves hygiene behaviors compared to standa…
Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Prevention
Last updated Jun 27, 2026 12:08 UTC