Inherited obesity
MONDO:0019182Also known as: genetic obesity, genetic obesity (disease), leanness, inherited, autosomal recessive, monogenic obesity, obesity, association with, Autosomal recessive, obesity, early-onset, susceptibility to, Autosomal recessive, obesity, late-onset, Autosomal recessive, obesity, mild, early-onset, Autosomal recessive
87 clinical trials for this condition and its sub-types, 8 tagged with Inherited obesity itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Inherited obesity
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Obesity due to CEP19 deficiency 0 trials
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Obesity due to SIM1 deficiency 0 trials
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Could a popular Weight-Loss drug help people with rare genetic obesity?
Disease control Recruiting nowThis study follows 175 adolescents and adults with monogenic obesity—a rare form caused by specific gene changes—who are taking semaglutide (Ozempic/Wegovy). Researchers will track weight and BMI changes over 4 years to see if the drug helps control weight in this group. The goal…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Rare leptin disorder patients gain access to experimental drug
Disease control Expanded accessThis program provides expanded access to REGN4461 (mibavademab) for people with rare diseases caused by deficient leptin signaling, such as generalized lipodystrophy and monogenic obesity. The drug aims to help control metabolic issues linked to these conditions. Participants rec…
Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New drug hopes to curb rare genetic obesity
Disease control Recruiting nowThis study tests an experimental drug called mibavademab in people with a rare form of obesity caused by a faulty leptin gene. The drug aims to help control hunger and body weight. Only 4 participants will be enrolled to see how well it works and if it is safe.
Phase 3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New hope for teens with rare obesity: weekly shot shows promise
Disease control Recruiting nowThis study looks at whether a once-weekly injection of semaglutide (2.4 mg) can help teenagers with monogenic obesity lose weight and feel better. About 70 teens aged 12 to 20 will take the drug along with diet and exercise changes for 68 weeks. The main goal is to see if at leas…
Sponsor: Prof. Dr. Martin Wabitsch • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Worldwide effort to track rare genetic obesity
Knowledge-focused Recruiting nowThis study creates a global database to collect information from people with genetic obesity. Researchers aim to learn how the condition progresses, what complications arise, and how different genetic types respond to standard treatments. Up to 5,000 participants will share data …
Sponsor: University of Ulm • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC