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New hope for rare leptin disorders: expanded access to REGN4461

NCT ID NCT04710056

First seen Nov 15, 2025 · Last updated May 22, 2026 · Updated 24 times

Summary

This program provides expanded access to REGN4461 for people with lipodystrophy or monogenic obesity caused by a lack of leptin signaling. The goal is to help manage these rare conditions by replacing the missing leptin signal. Participants must have a confirmed diagnosis and no other treatment options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Conditions

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