Inherited ichthyosis
MONDO:0015947Mendelian disorders of cornification affecting all or most of integument characterized by hyperkeratosis and/or scaling, caused by an inherited modification of the individual's genome.
Also known as: congenital ichthyosis of skin, genetic ichthyosis, hereditary ichthyosis (disease), inherited genetic ichthyosis, congenital ichthyosis, fish scale disease, fish skin, ichthyosis congenita
33 clinical trials for this condition and its sub-types, 6 tagged with Inherited ichthyosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Inherited ichthyosis
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Netherton syndrome 15 trials
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Autosomal recessive congenital ichthyosis 2 trials · 10 incl. sub-types
13 sub-types
- Exfoliative ichthyosis 0 trials · 6 incl. sub-types Sub-types →
- Autosomal recessive congenital ichthyosis 1 2 trials
- Congenital non-bullous ichthyosiform erythroderma 0 trials · 1 incl. sub-types Sub-types →
- Acral self-healing collodion baby 0 trials
- Autosomal recessive congenital ichthyosis 11 0 trials
- Autosomal recessive congenital ichthyosis 4A 0 trials Sub-types →
- Autosomal recessive congenital ichthyosis 5 0 trials
- Autosomal recessive congenital ichthyosis 8 0 trials
- Bathing suit ichthyosis 0 trials
- Ichthyosis, congenital, autosomal recessive 12 0 trials
- Ichthyosis, congenital, autosomal recessive 13 0 trials
- Ichthyosis, congenital, autosomal recessive 14 0 trials
- Self-healing collodion baby 0 trials Sub-types →
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Keratinopathic ichthyosis 0 trials · 7 incl. sub-types
5 sub-types
- Superficial epidermolytic ichthyosis 6 trials
- Epidermolytic ichthyosis 1 trial Sub-types →
- Congenital reticular ichthyosiform erythroderma 0 trials
- Epidermolytic nevus 0 trials
- Ichthyosis hystrix of Curth-Macklin 0 trials
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Ichthyosis vulgaris 3 trials
1 sub-type
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Recessive X-linked ichthyosis 2 trials
1 sub-type
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Peeling skin syndrome 1 trial
5 sub-types
- Acral peeling skin syndrome 0 trials
- Generalized peeling skin syndrome 0 trials Sub-types →
- Peeling skin syndrome 4 0 trials
- Peeling skin syndrome 5 0 trials
- Peeling skin syndrome 6 0 trials
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IFAP syndrome 0 trials
2 sub-types
- IFAP syndrome 1, with or without BRESHECK syndrome 0 trials
- IFAP syndrome 2 0 trials
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Ichthyosis hystrix 0 trials
2 sub-types
- Ichthyosis histrix, Lambert type 0 trials
- Ichthyosis hystrix of Curth-Macklin 0 trials
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Ichthyosis linearis circumflexa 0 trials
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Ichthyosis with erythrokeratoderma 0 trials
Most studied deeper sub-types
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Can a skin lotion tame the symptoms of a rare genetic disease?
Disease control Recruiting nowThis trial tests whether QRX003, a lotion applied to the skin, can reduce the redness, scaling, and itch caused by Netherton syndrome, a rare genetic condition. Participants apply the lotion twice daily for 3 months and visit the clinic every 4 to 6 weeks for checkups. The study …
Phase 2/3 • Sponsor: Quoin Pharmaceuticals • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Can a lotion calm the severe skin symptoms of netherton syndrome?
Disease control Recruiting nowThis trial tests whether QRX003 lotion, applied to the skin, can safely reduce the severity of Netherton syndrome, a rare genetic condition causing red, scaly skin and intense itching. Researchers will enroll about 20 people aged 14 and older who have the condition. Participants …
Phase 2/3 • Sponsor: Quoin Pharmaceuticals • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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New drug trial hopes to tame rare skin disease
Disease control Recruiting nowThis early-stage trial tests a new drug called BCX17725 in healthy volunteers and people with Netherton syndrome, a rare genetic skin condition. The study aims to check safety, how the drug moves through the body, and whether it can reduce skin redness and scaling. About 78 parti…
Phase 1 • Sponsor: BioCryst Pharmaceuticals • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New lotion shows promise for rare skin disorder
Disease control Recruiting nowThis study tests a lotion called QRX003 in people with Netherton Syndrome, a rare genetic skin condition. About 16 participants aged 4 and older will apply the lotion twice daily for 12 weeks. Researchers will check if it improves skin appearance and reduces itching.
Phase 2/3 • Sponsor: Quoin Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Cream wraps could soothe painful skin for ichthyosis patients
Symptom relief Recruiting nowThis study tests whether a series of three cream wraps can reduce skin discomfort in people with moderate to very severe hereditary ichthyosis. Participants will receive a therapeutic bath followed by application of a rich emollient cream and a plastic wrap for one hour. The main…
Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Could a common probiotic soothe IBS? new trial seeks answers
Symptom relief Recruiting nowThis study tests whether a probiotic called Saccharomyces boulardii can reduce symptoms of irritable bowel syndrome (IBS) in adults. About 406 people with non-constipated IBS will take either the probiotic or a placebo daily for 8 weeks. Researchers will measure changes in sympto…
Phase 3 • Sponsor: Biocodex • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Microbiome study seeks clues in rare skin condition
Knowledge-focused Recruiting nowThis study looks at the bacteria, fungi, and viruses living on the skin, in the gut, and in the mouth of people with Netherton syndrome, a rare condition that damages the skin barrier and often causes allergies. Researchers will compare these microbes to those of healthy voluntee…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC