Idiopathic nephrotic syndrome
MONDO:0018170Nephrotic syndrome for which no cause has been identified.
26 clinical trials for this condition and its sub-types, 13 tagged with Idiopathic nephrotic syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Idiopathic nephrotic syndrome
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4 sub-types
- Idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation 0 trials
- Idiopathic steroid-sensitive nephrotic syndrome with focal segmental hyalinosis 0 trials
- Idiopathic steroid-sensitive nephrotic syndrome with minimal change 0 trials
- Idiopathic steroid-sensitive nephrotic syndrome with secondary steroid resistance 0 trials
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Sporadic idiopathic steroid-resistant nephrotic syndrome 0 trials · 2 incl. sub-types
3 sub-types
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14 sub-types
- Familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation 0 trials
- Familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis 0 trials
- Familial idiopathic steroid-resistant nephrotic syndrome with minimal changes 0 trials
- Familial steroid-resistant nephrotic syndrome with sensorineural deafness 0 trials
- Focal segmental glomerulosclerosis 1 0 trials
- Nephrotic syndrome, type 10 0 trials
- Nephrotic syndrome, type 11 0 trials
- Nephrotic syndrome, type 12 0 trials
- Nephrotic syndrome, type 13 0 trials
- Nephrotic syndrome, type 2 0 trials
- Nephrotic syndrome, type 3 0 trials
- Nephrotic syndrome, type 6 0 trials
- Nephrotic syndrome, type 8 0 trials
- Nephrotic syndrome, type 9 0 trials
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Can a single Immune-Targeting drug quiet an autoimmune kidney disease?
Disease control OngoingThis trial tests whether rituximab, an infusion drug that calms certain immune cells, can help people with idiopathic membranous nephropathy and nephrotic syndrome. Participants receive either rituximab or a placebo, and the study tracks how many achieve a significant reduction i…
Phase 3 • Sponsor: Shoichi Maruyama MD PhD • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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CAR-T therapy aimed at tough kidney disease in kids — but trial never started
Disease control CancelledThis was a planned early-stage trial to test whether anti-CD19 CAR-T cells could safely help children with multi-drug resistant nephrotic syndrome, a serious kidney condition. The study was withdrawn before any patients were enrolled, so no data on safety or effectiveness were co…
Phase 1 • Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for kids with tough kidney disease: obinutuzumab may replace steroids
Disease control OngoingThis study tests a new drug called obinutuzumab in 100 children aged 1-18 with refractory nephrotic syndrome, a kidney condition causing swelling and protein loss. The drug targets immune cells to reduce disease flares and dependence on steroids and other medications. Researchers…
Sponsor: Children's Hospital of Chongqing Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Could less steroid be just as good for kids with kidney disease?
Disease control OngoingThis study tests whether a lower dose of the steroid prednisone can treat relapses of nephrotic syndrome in children as effectively as the standard dose. Fifty children aged 1 to 18 with active relapses will be randomly assigned to either the reduced-dose or standard-dose regimen…
Phase 3 • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New hope for kids with kidney disease: drug may cut relapses and steroids
Disease control OngoingThis study tests a drug called obinutuzumab against a standard treatment (MMF) in children and young adults with a kidney condition that causes frequent relapses. The goal is to see if obinutuzumab can keep the disease in remission longer and reduce the need for steroids. About 8…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Hidden calcium risk in Steroid-Treated kids
Knowledge-focused OngoingThis study looks at how often children with steroid-dependent nephrotic syndrome have high calcium levels in their urine (hypercalciuria). Researchers will check 50 children aged 2 to 16 who are on steroid treatment. The goal is simply to find out how common this condition is, no…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC