Hyperostosis
MONDO:0002185Excessive thickening of bone.
Also known as: bone hypertrophy, hypertrophy of bone, hypertrophy of bone (morphologic abnormality)
26 clinical trials for this condition and its sub-types, 2 tagged with Hyperostosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Hyperostosis
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Exostosis 2 trials · 16 incl. sub-types
3 sub-types
- Heel spur 11 trials
- Hereditary multiple osteochondromas 3 trials Sub-types →
- Heberden's node 0 trials
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Sclerosteosis 6 trials
2 sub-types
- Sclerosteosis 1 0 trials
- Sclerosteosis 2 0 trials
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Bone Paget disease 2 trials
5 sub-types
- Paget disease of bone 2, early-onset 0 trials
- Paget disease of bone 3 0 trials
- Paget disease of bone 6 0 trials
- Juvenile Paget disease 0 trials
- Paget disease of bone 4 0 trials
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Caffey disease 0 trials
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X-linked calvarial hyperostosis 0 trials
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Craniodiaphyseal dysplasia 0 trials
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Hyperostosis corticalis generalisata 0 trials
Most studied deeper sub-types
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Rare bone disease under the microscope: what causes melorheostosis?
Knowledge-focused Recruiting nowThis study follows adults with melorheostosis, a rare disease that causes bone thickening, pain, and joint problems. Researchers will track how the disease progresses over time, collect genetic samples from patients and their relatives, and look for biomarkers. The goal is to bet…
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Hunt for genes behind rare bone disease could unlock future treatments
Knowledge-focused Recruiting nowThis study aims to find the genes and genetic changes that cause craniometaphyseal dysplasia (CMD), a rare disorder that leads to abnormal bone growth in the skull and other bones. Researchers will analyze blood and tissue samples from 600 people, including affected individuals a…
Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC