Hereditary angioedema
MONDO:0019623Hereditary angioedema (HAE) is a genetic disease characterized by the occurrence of transitory and recurrent subcutaneous and/or submucosal edemas resulting in swelling and/or abdominal pain.
Also known as: HAE, familial angioneurotic edema, familial angioneurotic oedema, hereditary angioedema, hereditary angioneurotic edema, hereditary angioneurotic oedema, hereditary bradykinine-induced angioedema, hereditary non histamine-induced angioedema
61 clinical trials for this condition and its sub-types, 58 tagged with Hereditary angioedema itself.
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Browse by category →Sub-types of Hereditary angioedema
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Hereditary angioedema with C1Inh deficiency 14 trials · 32 incl. sub-types
2 sub-types
- Hereditary angioedema type 1 26 trials
- Hereditary angioedema type 2 26 trials
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Hereditary angioedema type 3 2 trials
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Angioedema, hereditary, 4 0 trials
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Angioedema, hereditary, 5 0 trials
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Angioedema, hereditary, 6 0 trials
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Angioedema, hereditary, 7 0 trials
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Angioedema, hereditary, 8 0 trials
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Could a daily pill stop hereditary angioedema attacks?
Disease control Stopped earlyThis trial tests whether an experimental oral medication, deucrictibant, can reduce the number of swelling attacks in people with hereditary angioedema (HAE) types I and II. Participants take either a low or high dose of the drug or a placebo for 12 weeks, and then may continue o…
Phase 2 • Sponsor: Pharvaris Netherlands B.V. • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New daily pill aims to stop HAE attacks, but trial cut short
Disease control Stopped earlyThis phase 2 trial tested KVD824, an oral pill, to prevent swelling attacks in people with hereditary angioedema types I and II. The study planned to compare three doses against a placebo over several months. However, the trial was terminated early with only 33 participants, so t…
Phase 2 • Sponsor: KalVista Pharmaceuticals, Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Scientists hunt for blood clues to tame unpredictable swelling attacks
Knowledge-focused Stopped earlyThis study aimed to find biomarkers (measurable substances in the blood) that could help doctors diagnose bradykinin angioedema and predict how severe attacks might be. The condition causes sudden, unpredictable swelling, and current tests don't work well for all types. Researche…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC