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Promising HAE prevention pill trial cut short

NCT ID NCT05055258

First seen May 16, 2026 · Last updated May 20, 2026 · Updated 1 time

Summary

This study tested three doses of an oral medication called KVD824 to see if it could prevent swelling attacks in people with hereditary angioedema (HAE) types I and II. The trial aimed to enroll adults with confirmed HAE, but was stopped early because not enough people signed up. As a result, the data is too limited to draw firm conclusions about the drug's effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • KalVista Investigative Site

    Birmingham, Alabama, 35294, United States

  • KalVista Investigative Site

    Scottsdale, Arizona, 85251, United States

  • KalVista Investigative Site

    La Jolla, California, 92093, United States

  • KalVista Investigative Site

    Santa Monica, California, 90404, United States

  • KalVista Investigative Site

    Centennial, Colorado, 80112, United States

  • KalVista Investigative Site

    Tampa, Florida, 33620, United States

  • KalVista Investigative Site

    Chevy Chase, Maryland, 20815, United States

  • KalVista Investigative Site

    Boston, Massachusetts, 02114, United States

  • KalVista Investigative Site

    St Louis, Missouri, 63110, United States

  • KalVista Investigative Site

    Cincinnati, Ohio, 45231, United States

  • KalVista Investigative Site

    Hershey, Pennsylvania, 17033, United States

  • KalVista Investigative Site

    Dallas, Texas, 75390, United States

  • KalVista Investigative Site

    Spokane, Washington, 99204, United States

  • KalVista Investigative Site

    Campbelltown, New South Wales, Australia

  • KalVista Investigative Site

    Sofia, Bulgaria

  • KalVista Investigative Site

    North York, Ontario, Canada

  • KalVista Investigative Site

    Brno, Czechia

  • KalVista Investigative Site

    Prague, Czechia

  • KalVista Investigative Site

    Grenoble, France

  • KalVista Investigative Site

    Paris, France

  • KalVista Investigative Site

    Mainz, Rhineland-Palatinate, Germany

  • KalVista Investigative Site

    Berlin, Germany

  • KalVista Investigative Site

    Frankfurt am Main, Germany

  • KalVista Investigative Site

    Budapest, Hungary

  • KalVista Investigative Site

    Milan, Italy

  • KalVista Investigative Site

    Padova, Italy

  • KalVista Investigative Site

    Grafton, Auckland, New Zealand

  • KalVista Investigative Site

    Skopje, North Macedonia

  • KalVista Investigative Site

    San Juan, Puerto Rico

  • KalVista Investigative Site

    Birmingham, United Kingdom

  • KalVista Investigative Site

    Leeds, United Kingdom

  • KalVista Investigative Site

    London, United Kingdom

  • KalVista Investigative Site

    Newcastle upon Tyne, United Kingdom

Conditions

Explore the condition pages connected to this study.